inhibits
P37861
predicate
Indicates that one entity prevents, restrains, or reduces the activity, effect, or occurrence of another entity.
All labels observed (16)
| Label | Occurrences |
|---|---|
| inhibitedBy | 67 |
| inhibits canonical | 44 |
| negativelyRegulates | 14 |
| thwarts | 9 |
| disables | 8 |
| decreasesSynthesisOf | 6 |
| isInhibitorOf | 6 |
| inhibitionOf | 4 |
| inhibitsEnzyme | 3 |
| impeded | 2 |
| inhibitsGrowthOf | 2 |
| inhibitsPathway | 2 |
| isInhibitedBy | 2 |
| repels | 2 |
| inhibitsExpressionOf | 1 |
| isStrongInhibitorOf | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: inhibits
Generated description
Indicates that one entity prevents, restrains, or reduces the activity, effect, or occurrence of another entity.
Sample triples (173)
| Subject | Object |
|---|---|
| Bruinen | Black Riders via predicate surface "thwarts" NERFINISHED ⓘ |
| ketoconazole | lanosterol 14α-demethylase NERFINISHED ⓘ |
| ketoconazole | ergosterol biosynthesis in fungi ⓘ |
| ketoconazole | CYP3A4 NERFINISHED ⓘ |
| ketoconazole | CYP17A1 NERFINISHED ⓘ |
| ketoconazole | CYP3A4 via predicate surface "isStrongInhibitorOf" ⓘ |
| itraconazole | CYP3A4 ⓘ |
| itraconazole | P-glycoprotein via predicate surface "isInhibitorOf" NERFINISHED ⓘ |
| clarithromycin | CYP3A4 NERFINISHED ⓘ |
| clarithromycin | P-glycoprotein NERFINISHED ⓘ |
| constitutive androstane receptor | androstanol via predicate surface "inhibitedBy" ⓘ |
| constitutive androstane receptor | androstenol via predicate surface "inhibitedBy" ⓘ |
| Pgp | verapamil via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Pgp | cyclosporine A via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Pgp | tariquidar via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Pgp | elacridar via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| quinidine | CYP2D6 ⓘ |
| quinidine | P-glycoprotein NERFINISHED ⓘ |
|
mitoxantrone
surface form:
Mitoxantrone
|
topoisomerase II ⓘ |
| Airplane Mode | cellular connectivity via predicate surface "disables" ⓘ |
| Airplane Mode | mobile data via predicate surface "disables" ⓘ |
| Airplane Mode | voice calls via predicate surface "disables" ⓘ |
| Airplane Mode | SMS messaging via predicate surface "disables" ⓘ |
| Airplane Mode | Wi‑Fi via predicate surface "disables" ⓘ |
| Airplane Mode | Bluetooth via predicate surface "disables" NERFINISHED ⓘ |
| Airplane Mode | NFC via predicate surface "disables" ⓘ |
| Airplane Mode | GPS-assisted cellular data features via predicate surface "disables" ⓘ |
| CD46 | complement cascade on host cells ⓘ |
| Melatonin | light exposure via predicate surface "isInhibitedBy" ⓘ |
| topiramate | carbonic anhydrase isoenzymes II and IV ⓘ |
| Gi-coupled GPCR | cAMP production via predicate surface "negativelyRegulates" ⓘ |
| somatostatin receptor | cyclic AMP biosynthetic process via predicate surface "negativelyRegulates" ⓘ |
| somatostatin receptor | hormone secretion via predicate surface "negativelyRegulates" ⓘ |
| somatostatin receptor | neurotransmitter release via predicate surface "negativelyRegulates" ⓘ |
| somatostatin receptor | cell proliferation via predicate surface "negativelyRegulates" ⓘ |
|
MAGL enzyme
surface form:
MAGL
|
JZL184 via predicate surface "inhibitedBy" ⓘ |
|
MAGL enzyme
surface form:
MAGL
|
KML29 via predicate surface "inhibitedBy" ⓘ |
|
MAGL enzyme
surface form:
MAGL
|
MJN110 via predicate surface "inhibitedBy" ⓘ |
|
MAGL enzyme
surface form:
MAGL
|
URB602 via predicate surface "inhibitedBy" ⓘ |
|
MAGL enzyme
surface form:
MAGL
|
organophosphorus inhibitors via predicate surface "inhibitedBy" ⓘ |
| DAGL enzyme | selective DAGL inhibitors via predicate surface "inhibitedBy" ⓘ |
| DAGL enzyme | tetrahydrolipstatin (orlistat, weakly) via predicate surface "inhibitedBy" NERFINISHED ⓘ |
|
GNAI3 gene (for Gαi3 in humans)
surface form:
GNAI3
|
adenylate cyclase ⓘ |
|
GNAI3 gene (for Gαi3 in humans)
surface form:
GNAI3
|
cAMP biosynthetic process via predicate surface "negativelyRegulates" ⓘ |
| Src family kinases | dasatinib via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Src family kinases | bosutinib via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Src family kinases | saracatinib via predicate surface "inhibitedBy" NERFINISHED ⓘ |
| Src family kinases | ponatinib via predicate surface "inhibitedBy" ⓘ |
| Src family kinases | PP2 (experimental inhibitor) via predicate surface "inhibitedBy" ⓘ |
| Src family kinases | SU6656 (experimental inhibitor) via predicate surface "inhibitedBy" ⓘ |