somatostatin receptor

E874317
G protein–coupled receptor membrane receptor neurotransmitter receptor protein family

A somatostatin receptor is a G protein–coupled membrane receptor that binds the peptide hormone somatostatin to inhibit hormone secretion and modulate neurotransmission and cell proliferation.

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Statements (54)

Predicate Object
instanceOf G protein–coupled receptor ⓘ
membrane receptor ⓘ
neurotransmitter receptor ⓘ
protein family ⓘ
belongsToPathway G protein–coupled receptor signaling pathway ⓘ
inhibitory G protein signaling pathway ⓘ
couplesTo Gi protein ⓘ
Go protein ⓘ
hasBiologicalProcess inhibition of adenylate cyclase activity ⓘ
inhibition of hormone secretion ⓘ
modulation of neurotransmission ⓘ
regulation of calcium channel activity ⓘ
regulation of cell proliferation ⓘ
regulation of potassium channel activity ⓘ
hasCellularLocation cell surface ⓘ
plasma membrane ⓘ
hasComponent seven transmembrane helices ⓘ
hasLigand DOTATATE NERFINISHED ⓘ
DOTATOC NERFINISHED ⓘ
lanreotide NERFINISHED ⓘ
octreotide ⓘ
pasireotide NERFINISHED ⓘ
somatostatin ⓘ
somatostatin-14 ⓘ
somatostatin-28 NERFINISHED ⓘ
hasMolecularFunction G protein–coupled receptor activity ⓘ
signal transducer activity ⓘ
somatostatin binding ⓘ
hasSubtype SSTR1 ⓘ
SSTR2 NERFINISHED ⓘ
SSTR3 NERFINISHED ⓘ
SSTR4 NERFINISHED ⓘ
SSTR5 NERFINISHED ⓘ
isEncodedBy SSTR1 gene NERFINISHED ⓘ
SSTR2 gene NERFINISHED ⓘ
SSTR3 gene NERFINISHED ⓘ
SSTR4 gene NERFINISHED ⓘ
SSTR5 gene NERFINISHED ⓘ
isExpressedIn central nervous system ⓘ
endocrine tumors ⓘ
gastrointestinal tract ⓘ
hypothalamus NERFINISHED ⓘ
pancreatic islet cells ⓘ
pituitary gland ⓘ
isTargetOf peptide receptor radionuclide therapy ⓘ
radiolabeled diagnostic agents ⓘ
somatostatin analogs ⓘ
isUsedIn imaging of neuroendocrine tumors ⓘ
treatment of acromegaly ⓘ
treatment of neuroendocrine tumors ⓘ
negativelyRegulates cell proliferation ⓘ
cyclic AMP biosynthetic process ⓘ
hormone secretion ⓘ
neurotransmitter release ⓘ

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Gi protein → couplesToReceptor → somatostatin receptor ⓘ