inhibits
P37861
predicate
Indicates that one entity prevents, restrains, or reduces the activity, effect, or occurrence of another entity.
All labels observed (16)
| Label | Occurrences |
|---|---|
| inhibitedBy | 67 |
| inhibits canonical | 44 |
| negativelyRegulates | 14 |
| thwarts | 9 |
| disables | 8 |
| decreasesSynthesisOf | 6 |
| isInhibitorOf | 6 |
| inhibitionOf | 4 |
| inhibitsEnzyme | 3 |
| impeded | 2 |
| inhibitsGrowthOf | 2 |
| inhibitsPathway | 2 |
| isInhibitedBy | 2 |
| repels | 2 |
| inhibitsExpressionOf | 1 |
| isStrongInhibitorOf | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: inhibits
Generated description
Indicates that one entity prevents, restrains, or reduces the activity, effect, or occurrence of another entity.
Sample triples (173)
| Subject | Object |
|---|---|
| Perjeta | HER2 dimerization ⓘ |
| Morgiana | the thieves' plan to kill Ali Baba via predicate surface "thwarts" ⓘ |
| Morgiana | the thieves' infiltration of Ali Baba's house via predicate surface "thwarts" ⓘ |
| zanamivir | influenza A neuraminidase ⓘ |
| zanamivir | influenza B neuraminidase ⓘ |
| insulin | hepatic gluconeogenesis ⓘ |
| insulin | glycogenolysis ⓘ |
| insulin | lipolysis ⓘ |
| insulin | ketogenesis ⓘ |
| Tagetes | nematodes via predicate surface "repels" ⓘ |
| Tagetes | some insect pests via predicate surface "repels" ⓘ |
| programmed death-ligand 1 | T cell proliferation ⓘ |
| programmed death-ligand 1 | T cell cytokine production ⓘ |
| programmed death-ligand 1 | T cell cytotoxicity ⓘ |
| CYP3A4 | ketoconazole via predicate surface "inhibitedBy" ⓘ |
| CYP3A4 | itraconazole via predicate surface "inhibitedBy" ⓘ |
| CYP3A4 | clarithromycin via predicate surface "inhibitedBy" ⓘ |
| CYP3A4 | ritonavir via predicate surface "inhibitedBy" ⓘ |
| CYP3A4 | grapefruit juice via predicate surface "inhibitedBy" ⓘ |
| CYP2J2 | ketoconazole via predicate surface "inhibitedBy" ⓘ |
| CYP2J2 | fluconazole via predicate surface "inhibitedBy" ⓘ |
| CYP2J2 | itraconazole via predicate surface "inhibitedBy" ⓘ |
| CYP2J2 | danazol via predicate surface "inhibitedBy" ⓘ |
| CYP2J2 | grapefruit juice components via predicate surface "inhibitedBy" ⓘ |
| BCRP | elacridar via predicate surface "inhibitedBy" ⓘ |
| BCRP | Ko143 via predicate surface "inhibitedBy" ⓘ |
| BCRP | tyrosine kinase inhibitors via predicate surface "inhibitedBy" ⓘ |
| BCRP | cyclosporine A via predicate surface "inhibitedBy" ⓘ |
| warfarin | coagulation factor II (prothrombin) via predicate surface "decreasesSynthesisOf" ⓘ |
| warfarin | coagulation factor VII via predicate surface "decreasesSynthesisOf" ⓘ |
| warfarin | coagulation factor IX via predicate surface "decreasesSynthesisOf" ⓘ |
| warfarin | coagulation factor X via predicate surface "decreasesSynthesisOf" ⓘ |
| warfarin | protein C via predicate surface "decreasesSynthesisOf" ⓘ |
| warfarin | protein S via predicate surface "decreasesSynthesisOf" ⓘ |
| apixaban | coagulation factor Xa ⓘ |
| dabigatran | thrombin ⓘ |
| dabigatran | factor IIa ⓘ |
| Gi protein | adenylyl cyclase ⓘ |
| Gi protein | cAMP levels via predicate surface "negativelyRegulates" ⓘ |
| Bruton tyrosine kinase | covalent BTK inhibitors via predicate surface "inhibitedBy" ⓘ |
| Bruton tyrosine kinase | non-covalent BTK inhibitors via predicate surface "inhibitedBy" ⓘ |
| Lowenstein–Jensen medium | most Gram-positive bacteria via predicate surface "inhibitsGrowthOf" ⓘ |
| Lowenstein–Jensen medium | most Gram-negative bacteria via predicate surface "inhibitsGrowthOf" ⓘ |
| CB2 receptor | adenylate cyclase ⓘ |
| Second Cataract of the Nile | riverine navigation via predicate surface "impeded" ⓘ |
| Yersinia outer proteins | phagocytic uptake by macrophages via predicate surface "inhibitionOf" ⓘ |
| Yersinia outer proteins | pro-inflammatory cytokine production via predicate surface "inhibitionOf" ⓘ |
| Yersinia outer proteins | NF-kappaB signaling via predicate surface "inhibitionOf" ⓘ |
| Yersinia outer proteins | MAPK signaling pathways via predicate surface "inhibitionOf" ⓘ |
| Dnieper Rapids | navigation on the Dnieper River via predicate surface "impeded" ⓘ |