Triple
T10214776
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | CYP3A4 |
E242412
|
entity |
| Predicate | inhibitedBy |
P37861
|
FINISHED |
| Object |
ketoconazole
Ketoconazole is an imidazole antifungal medication that inhibits ergosterol synthesis and strongly blocks CYP3A4-mediated drug metabolism.
|
E850010
|
NE FINISHED |
How this triple was built (5 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: ketoconazole | Statement: [CYP3A4, inhibitedBy, ketoconazole]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: ketoconazole Context triple: [CYP3A4, inhibitedBy, ketoconazole]
-
A.
fluconazole
Fluconazole is a triazole antifungal medication commonly used to treat and prevent a wide range of Candida infections in humans.
-
B.
voriconazole
Voriconazole is a broad-spectrum triazole antifungal medication commonly used to treat serious invasive fungal infections, particularly those caused by Aspergillus species.
-
C.
posaconazole
Posaconazole is a broad-spectrum triazole antifungal medication commonly used to prevent and treat serious invasive fungal infections, particularly in immunocompromised patients.
-
D.
amphotericin B
Amphotericin B is a broad-spectrum antifungal medication primarily used to treat severe, systemic fungal infections.
-
E.
Kotramide
Kotramide was a medieval Armenian noblewoman known primarily as the wife of King Ashot I Bagratuni, the first king of the Bagratid Kingdom of Armenia.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: ketoconazole Triple: [CYP3A4, inhibitedBy, ketoconazole]
Generated description
Ketoconazole is an imidazole antifungal medication that inhibits ergosterol synthesis and strongly blocks CYP3A4-mediated drug metabolism.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: ketoconazole Target entity description: Ketoconazole is an imidazole antifungal medication that inhibits ergosterol synthesis and strongly blocks CYP3A4-mediated drug metabolism.
-
A.
fluconazole
Fluconazole is a triazole antifungal medication commonly used to treat and prevent a wide range of Candida infections in humans.
-
B.
voriconazole
Voriconazole is a broad-spectrum triazole antifungal medication commonly used to treat serious invasive fungal infections, particularly those caused by Aspergillus species.
-
C.
posaconazole
Posaconazole is a broad-spectrum triazole antifungal medication commonly used to prevent and treat serious invasive fungal infections, particularly in immunocompromised patients.
-
D.
amphotericin B
Amphotericin B is a broad-spectrum antifungal medication primarily used to treat severe, systemic fungal infections.
-
E.
Kotramide
Kotramide was a medieval Armenian noblewoman known primarily as the wife of King Ashot I Bagratuni, the first king of the Bagratid Kingdom of Armenia.
- F. None of above. chosen
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: inhibitedBy Context triple: [CYP3A4, inhibitedBy, ketoconazole]
-
A.
inhibits
chosen
Indicates that one entity prevents, restrains, or reduces the activity, effect, or occurrence of another entity.
-
B.
airedIn
Indicates that a media work was broadcast or shown during a specific time period or in a particular airing context.
-
C.
suppressedIn
Indicates that one entity’s presence, activity, or expression is reduced, inhibited, or prevented by another entity or condition.
-
D.
prohibits
Indicates that one entity forbids or disallows another entity from performing a specific action or being in a certain state.
-
E.
forcedBy
Indicates that an entity is compelled or coerced into an action or state by another entity.
- F. None of above.
Provenance (6 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d381ae26c48190985abd0e25ee5d04 |
completed | April 6, 2026, 9:49 a.m. |
| NER | Named-entity recognition | batch_69d3aa273bdc8190bc4cf67a7923cebc |
completed | April 6, 2026, 12:42 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69d652ea80dc81908bc65ee2ec390467 |
completed | April 8, 2026, 1:06 p.m. |
| NEDg | Description generation | batch_69d657818b008190a24170717cff53b9 |
completed | April 8, 2026, 1:26 p.m. |
| NED2 | Entity disambiguation (via description) | batch_69d65835a11c819083d069ab0f644d4c |
completed | April 8, 2026, 1:29 p.m. |
| PD | Predicate disambiguation | batch_69d39559e5ac8190b88eca75956b7e6a |
completed | April 6, 2026, 11:13 a.m. |
Created at: April 6, 2026, 11:04 a.m.