hasMolecularTarget
P37016
predicate
Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
All labels observed (28)
| Label | Occurrences |
|---|---|
| targetOfDrug | 48 |
| hasMolecularTarget canonical | 28 |
| therapeuticTargetOf | 15 |
| isTargetOfDrug | 14 |
| drugTarget | 13 |
| hasPharmacologicTarget | 5 |
| isDrugTargetFor | 5 |
| isDrugTargetOf | 5 |
| isTherapeuticTargetOf | 5 |
| targetMolecule | 5 |
| drugTargetFor | 4 |
| molecularTarget | 4 |
| affectsMolecularTarget | 3 |
| hasMolecularTargetClass | 3 |
| hasMolecularTargetType | 3 |
| targetsEnzyme | 3 |
| isTargetOfDrugClass | 2 |
| ligandOf | 2 |
| targetsDrug | 2 |
| targetsMolecule | 2 |
| therapeuticTarget | 2 |
| biologicTarget | 1 |
| drugMechanismStudied | 1 |
| hasPharmacologicalTargetCell | 1 |
| hasPrimaryMolecularTarget | 1 |
| molecularTargetClass | 1 |
| pertuzumabTarget | 1 |
| trastuzumabTarget | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: hasMolecularTarget
Generated description
Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
Sample triples (180)
| Subject | Object |
|---|---|
| HIV-1 | protease via predicate surface "drugTarget" ⓘ |
| HIV-1 | integrase via predicate surface "drugTarget" ⓘ |
| HIV-1 | entry receptors via predicate surface "drugTarget" ⓘ |
| aromatic L-amino acid decarboxylase | carbidopa via predicate surface "isTargetOfDrug" ⓘ |
| aromatic L-amino acid decarboxylase | benserazide via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| aromatic L-amino acid decarboxylase | methyldopa via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | nivolumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | pembrolizumab via predicate surface "targetOfDrug" ⓘ |
| programmed cell death protein 1 | cemiplimab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | tislelizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | toripalimab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | camrelizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | sintilimab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| programmed cell death protein 1 | spartalizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| PD-1 | nivolumab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | pembrolizumab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | cemiplimab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | spartalizumab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | tislelizumab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | camrelizumab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | toripalimab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
| PD-1 | sintilimab via predicate surface "isTargetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
bevacizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
ranibizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
aflibercept via predicate surface "targetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
brolucizumab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
pegaptanib via predicate surface "targetOfDrug" NERFINISHED ⓘ |
|
vascular endothelial growth factor A
surface form:
Vascular endothelial growth factor A
|
faricimab via predicate surface "targetOfDrug" NERFINISHED ⓘ |
| TENAYA | VEGF-A via predicate surface "drugTarget" NERFINISHED ⓘ |
| TENAYA | Angiopoietin-2 via predicate surface "drugTarget" NERFINISHED ⓘ |
| tumor necrosis factor alpha | infliximab via predicate surface "therapeuticTargetOf" NERFINISHED ⓘ |
| tumor necrosis factor alpha | adalimumab via predicate surface "therapeuticTargetOf" NERFINISHED ⓘ |
| tumor necrosis factor alpha | etanercept via predicate surface "therapeuticTargetOf" NERFINISHED ⓘ |
| tumor necrosis factor alpha | golimumab via predicate surface "therapeuticTargetOf" NERFINISHED ⓘ |
| tumor necrosis factor alpha | certolizumab pegol via predicate surface "therapeuticTargetOf" NERFINISHED ⓘ |
| Andexxa | factor Xa inhibitors via predicate surface "hasPharmacologicTarget" ⓘ |
| Andexxa | rivaroxaban via predicate surface "hasPharmacologicTarget" NERFINISHED ⓘ |
| Andexxa | apixaban via predicate surface "hasPharmacologicTarget" ⓘ |
| Andexxa | edoxaban via predicate surface "hasPharmacologicTarget" NERFINISHED ⓘ |
| Andexxa | enoxaparin via predicate surface "hasPharmacologicTarget" ⓘ |
| Ondexxya | apixaban via predicate surface "targetsDrug" NERFINISHED ⓘ |
| Ondexxya | rivaroxaban via predicate surface "targetsDrug" NERFINISHED ⓘ |
| Ondexxya | factor Xa inhibitors bound to factor Xa ⓘ |
| Bortecad | protein complex via predicate surface "hasMolecularTargetType" ⓘ |
| pomalidomide | cereblon via predicate surface "molecularTarget" NERFINISHED ⓘ |
| Ofatumumab | B‑cell surface antigen via predicate surface "hasMolecularTargetClass" ⓘ |
| idarucizumab | direct thrombin inhibitor dabigatran via predicate surface "hasMolecularTargetClass" ⓘ |
| topiramate | voltage-gated sodium channels via predicate surface "affectsMolecularTarget" ⓘ |
| topiramate | GABA-A receptors via predicate surface "affectsMolecularTarget" ⓘ |
| topiramate | AMPA/kainate glutamate receptors via predicate surface "affectsMolecularTarget" ⓘ |