Bortecad
E852352
Bortecad is a branded pharmaceutical formulation of the proteasome inhibitor bortezomib, used primarily in the treatment of multiple myeloma and certain lymphomas.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Bortecad canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T10292127 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Bortecad Context triple: [bortezomib, hasTradeName, Bortecad]
-
A.
Kotramide
Kotramide was a medieval Armenian noblewoman known primarily as the wife of King Ashot I Bagratuni, the first king of the Bagratid Kingdom of Armenia.
-
B.
Balemartine
Balemartine is a small coastal village located on the island of Tiree in Scotland’s Inner Hebrides.
-
C.
Benso
Benso is the aristocratic family name of Camillo Benso, Count of Cavour, a leading statesman of the Italian unification.
-
D.
Corbenic
Corbenic is the legendary Grail Castle in Arthurian romance, famed as the mystical stronghold where the Holy Grail is kept.
-
E.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Bortecad Target entity description: Bortecad is a branded pharmaceutical formulation of the proteasome inhibitor bortezomib, used primarily in the treatment of multiple myeloma and certain lymphomas.
-
A.
Kotramide
Kotramide was a medieval Armenian noblewoman known primarily as the wife of King Ashot I Bagratuni, the first king of the Bagratid Kingdom of Armenia.
-
B.
Balemartine
Balemartine is a small coastal village located on the island of Tiree in Scotland’s Inner Hebrides.
-
C.
Benso
Benso is the aristocratic family name of Camillo Benso, Count of Cavour, a leading statesman of the Italian unification.
-
D.
Corbenic
Corbenic is the legendary Grail Castle in Arthurian romance, famed as the mystical stronghold where the Holy Grail is kept.
-
E.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
- F. None of above. chosen
Statements (35)
| Predicate | Object |
|---|---|
| instanceOf |
bortezomib-containing product
ⓘ
branded formulation ⓘ pharmaceutical drug ⓘ |
| belongsToRegimen | bortezomib-based chemotherapy regimen ⓘ |
| contraindicatedIn | severe hypersensitivity to bortezomib ⓘ |
| drugClass | antineoplastic agent ⓘ |
| hasActiveIngredient | bortezomib ⓘ |
| hasAdverseEffect |
anemia
ⓘ
fatigue ⓘ gastrointestinal disorders ⓘ neutropenia ⓘ peripheral neuropathy ⓘ thrombocytopenia ⓘ |
| hasATCLevel3Class | proteasome inhibitors ⓘ |
| hasDosageForm |
injectable
ⓘ
powder for solution for injection ⓘ |
| hasMolecularTargetType | protein complex ⓘ |
| hasPharmacologicalClass | proteasome inhibitor ⓘ |
| indicatedForLineOfTherapy |
first-line treatment of multiple myeloma in combination regimens
ⓘ
treatment of relapsed multiple myeloma ⓘ |
| isBrandOf | bortezomib NERFINISHED ⓘ |
| mayBeUsedInCombinationWith |
dexamethasone
NERFINISHED
ⓘ
melphalan NERFINISHED ⓘ prednisone ⓘ |
| mechanismOfAction | reversible inhibition of 26S proteasome ⓘ |
| metabolism | hepatic ⓘ |
| routeOfAdministration |
intravenous
ⓘ
subcutaneous ⓘ |
| targets |
26S proteasome
ⓘ
proteasome beta 5 subunit ⓘ |
| therapeuticArea |
hematology
ⓘ
oncology ⓘ |
| usedFor |
lymphoma
ⓘ
mantle cell lymphoma ⓘ multiple myeloma ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Bortecad Description of subject: Bortecad is a branded pharmaceutical formulation of the proteasome inhibitor bortezomib, used primarily in the treatment of multiple myeloma and certain lymphomas.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.