Bortecad

E852352

Bortecad is a branded pharmaceutical formulation of the proteasome inhibitor bortezomib, used primarily in the treatment of multiple myeloma and certain lymphomas.

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Statements (35)

Predicate Object
instanceOf bortezomib-containing product
branded formulation
pharmaceutical drug
belongsToRegimen bortezomib-based chemotherapy regimen
contraindicatedIn severe hypersensitivity to bortezomib
drugClass antineoplastic agent
hasActiveIngredient bortezomib
hasAdverseEffect anemia
fatigue
gastrointestinal disorders
neutropenia
peripheral neuropathy
thrombocytopenia
hasATCLevel3Class proteasome inhibitors
hasDosageForm injectable
powder for solution for injection
hasMolecularTargetType protein complex
hasPharmacologicalClass proteasome inhibitor
indicatedForLineOfTherapy first-line treatment of multiple myeloma in combination regimens
treatment of relapsed multiple myeloma
isBrandOf bortezomib NERFINISHED
mayBeUsedInCombinationWith dexamethasone NERFINISHED
melphalan NERFINISHED
prednisone
mechanismOfAction reversible inhibition of 26S proteasome
metabolism hepatic
routeOfAdministration intravenous
subcutaneous
targets 26S proteasome
proteasome beta 5 subunit
therapeuticArea hematology
oncology
usedFor lymphoma
mantle cell lymphoma
multiple myeloma

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

bortezomib hasTradeName Bortecad