Bortecad
E852352
Bortecad is a branded pharmaceutical formulation of the proteasome inhibitor bortezomib, used primarily in the treatment of multiple myeloma and certain lymphomas.
Statements (35)
| Predicate | Object |
|---|---|
| instanceOf |
bortezomib-containing product
ⓘ
branded formulation ⓘ pharmaceutical drug ⓘ |
| belongsToRegimen | bortezomib-based chemotherapy regimen ⓘ |
| contraindicatedIn | severe hypersensitivity to bortezomib ⓘ |
| drugClass | antineoplastic agent ⓘ |
| hasActiveIngredient | bortezomib ⓘ |
| hasAdverseEffect |
anemia
ⓘ
fatigue ⓘ gastrointestinal disorders ⓘ neutropenia ⓘ peripheral neuropathy ⓘ thrombocytopenia ⓘ |
| hasATCLevel3Class | proteasome inhibitors ⓘ |
| hasDosageForm |
injectable
ⓘ
powder for solution for injection ⓘ |
| hasMolecularTargetType | protein complex ⓘ |
| hasPharmacologicalClass | proteasome inhibitor ⓘ |
| indicatedForLineOfTherapy |
first-line treatment of multiple myeloma in combination regimens
ⓘ
treatment of relapsed multiple myeloma ⓘ |
| isBrandOf | bortezomib NERFINISHED ⓘ |
| mayBeUsedInCombinationWith |
dexamethasone
NERFINISHED
ⓘ
melphalan NERFINISHED ⓘ prednisone ⓘ |
| mechanismOfAction | reversible inhibition of 26S proteasome ⓘ |
| metabolism | hepatic ⓘ |
| routeOfAdministration |
intravenous
ⓘ
subcutaneous ⓘ |
| targets |
26S proteasome
ⓘ
proteasome beta 5 subunit ⓘ |
| therapeuticArea |
hematology
ⓘ
oncology ⓘ |
| usedFor |
lymphoma
ⓘ
mantle cell lymphoma ⓘ multiple myeloma ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.