Yersinia pestis

E72523

Gram-negative bacterium bacterium coccobacillus facultative anaerobe pathogen

Yersinia pestis is a highly virulent bacterium responsible for plague, including the historic pandemics of bubonic, septicemic, and pneumonic forms.

Predicate	Object
instanceOf	Gram-negative bacterium → bacterium → coccobacillus → facultative anaerobe → pathogen →
antibioticClassUsed	aminoglycosides → fluoroquinolones → tetracyclines →
associatedPandemic	Black Death → Justinianic Plague → Third Plague Pandemic →
biosafetyConcern	potential bioterrorism agent →
biosafetyLevel	BSL-3 →
causes	bubonic plague → plague → pneumonic plague → septicemic plague →
CDCClassification	Category A bioterrorism agent →
class	Gammaproteobacteria →
discoveredBy	Alexandre Yersin →
discoveryYear	1894 →
domain	Bacteria →
family	Yersiniaceae →
formerlyNamed	Pasteurella pestis →
genomeType	circular chromosome →
genus	Yersinia →
GramStain	Gram-negative →
hasPlasmid	pCD1 → pMT1 → pPCP1 →
humanDisease	acute febrile illness →
motility	non-motile →
naturalHabitat	rodent-flea ecological cycle →
order	Enterobacterales →
oxygenRequirement	facultative anaerobic →
phylum	Pseudomonadota →
primaryReservoir	rodents →
shape	short rod →
sporeForming	non-spore-forming →
stainingCharacteristic	bipolar staining →
taxonRank	species →
transmissionRoute	contact with infected animals → flea bite → inhalation of infectious droplets →
transmissionVector	fleas →
treatment	antibiotics →
virulenceFactor	F1 capsule antigen → Yersinia outer proteins → lipopolysaccharide endotoxin → type III secretion system →
zoonotic	true →

Subject (surface form when different)	Predicate
Black Death → Great Plague of London →	hasCause
Third Plague Pandemic →	causativeAgent
Yersinia pestis ("Pasteurella pestis") →	formerlyNamed
Justinianic Plague →	hasCauseAgent
Justinianic Plague ("bubonic plague") →	hasDiseaseType
Unit 731 →	notablePathogen