Loxo Oncology (acquired)

E133655

Loxo Oncology (acquired) is a biotechnology company focused on developing targeted cancer therapies, particularly for tumors driven by specific genetic alterations.

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Loxo Oncology (acquired) canonical 1

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Predicate Object
instanceOf biotechnology company
oncology company
acquiredBy Eli Lilly and Company
acquisitionAnnouncedOn 2019-01-07
acquisitionCompletedOn 2019-02-15
acquisitionValueUSD 8000000000
coFounder David Hyman
Joshua Bilenker
Keith Flaherty
collaborationPurpose development and commercialization of larotrectinib
country United States of America
surface form: United States
developedDrug LOXO-195
LOXO-292
LOXO-305
larotrectinib
selpercatinib
drugTarget BTK
RET alterations
TRK fusion proteins
focusesOn precision oncology
small molecule therapies
targeted cancer therapies
foundedIn 2013
headquartersLocation Stamford, Connecticut
industry biotechnology
pharmaceuticals
laterHeadquartersLocation Stamford, Connecticut
surface form: Stamford, Connecticut, United States
leadProduct larotrectinib
leadProductAlsoKnownAs LOXO-195
surface form: LOXO-101
leadProductIndication NTRK gene fusion-positive solid tumors
leadProductMarketedName Vitrakvi
listedOn NASDAQ
notableCollaboration Bayer
parentOrganizationAfterAcquisition Eli Lilly and Company
regulatoryAgencyApproval Food and Drug Administration
surface form: U.S. Food and Drug Administration
regulatoryApprovalFor larotrectinib
regulatoryApprovalYear 2018
regulatoryMilestone first TRK inhibitor approved in the United States
researchApproach genomics-driven drug discovery
tumor-agnostic therapy development
secondMajorProduct selpercatinib
secondMajorProductAlsoKnownAs LOXO-292
secondMajorProductIndication RET-altered lung and thyroid cancers
secondMajorProductMarketedName Retevmo
specializesIn oncogenic driver mutations
tumors driven by specific genetic alterations
tickerSymbolBeforeAcquisition LOXO

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Eli Lilly and Company hasSubsidiary Loxo Oncology (acquired)