Triple
T6003729
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Loxo Oncology |
E133655
|
entity |
| Predicate | leadProduct |
P68639
|
FINISHED |
| Object | larotrectinib |
E561035
|
NE FINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: larotrectinib | Statement: [Loxo Oncology, leadProduct, larotrectinib]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: larotrectinib Context triple: [Loxo Oncology, leadProduct, larotrectinib]
-
A.
larotrectinib
chosen
Larotrectinib is a targeted cancer therapy that selectively inhibits TRK fusion proteins and is used to treat solid tumors harboring NTRK gene fusions regardless of tumor site.
-
B.
selpercatinib
Selpercatinib is a targeted cancer therapy drug that selectively inhibits RET kinase to treat certain RET-altered thyroid and non-small cell lung cancers.
-
C.
Imfinzi
Imfinzi is a prescription immunotherapy drug (durvalumab) developed by AstraZeneca, primarily used to treat certain types of lung and bladder cancers by helping the immune system attack cancer cells.
-
D.
Lynparza
Lynparza is a targeted cancer therapy (a PARP inhibitor) used primarily to treat certain types of ovarian, breast, pancreatic, and prostate cancers associated with BRCA mutations.
-
E.
Vitrakvi
Vitrakvi is a targeted cancer therapy (larotrectinib) used to treat solid tumors that have a specific NTRK gene fusion, regardless of the tumor’s location in the body.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: leadProduct Context triple: [Loxo Oncology, leadProduct, larotrectinib]
-
A.
leadsInto
Indicates that one entity serves as an entry or transition point that directly connects or opens into another entity.
-
B.
leadsOrder
Indicates that one entity holds primary responsibility or authority over the order associated with another entity.
-
C.
leadSingle
Indicates that an entity serves as the primary or featured performer, contributor, or focus in a single work or instance.
-
D.
leads
Indicates having primary responsibility for directing, guiding, or managing another entity or group toward a goal or outcome.
-
E.
helpsLead
Indicates that one entity assists or contributes to another entity’s act of leading or guiding.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69c00872444c8190bfaf1739dcec765c |
completed | March 22, 2026, 3:19 p.m. |
| NER | Named-entity recognition | batch_69c04f0f63148190826198281dce3713 |
completed | March 22, 2026, 8:20 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69c11365741c819097a43a49dd2428c1 |
completed | March 23, 2026, 10:18 a.m. |
| PD | Predicate disambiguation | batch_69c049e3316c819087ea635fa7ee8472 |
completed | March 22, 2026, 7:58 p.m. |
| PDg | Predicate description generation | batch_69c04e8c5bfc8190b986a7071d1b23e3 |
completed | March 22, 2026, 8:18 p.m. |
Created at: March 22, 2026, 4:06 p.m.