Triple

T6003728
Position Surface form Disambiguated ID Type / Status
Subject Loxo Oncology E133655 entity
Predicate drugTarget P37016 FINISHED
Object BTK
BTK (Bruton’s tyrosine kinase) is a key signaling enzyme in B cells and a major therapeutic target in certain blood cancers and autoimmune diseases.
 E561038 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: BTK | Statement: [Loxo Oncology, drugTarget, BTK]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: BTK
Context triple: [Loxo Oncology, drugTarget, BTK]
  • A. Batta
    Batta is an ethnic group indigenous to northeastern Nigeria, particularly associated with Adamawa State.
  • B. Bt
    Bt is the post-nominal abbreviation for a baronetcy title in the British honours system, indicating that the holder is a baronet.
  • C. Batz
    Batz is a German surname most notably associated with World War II Luftwaffe fighter ace Wilhelm Batz.
  • D. Bax
    Bax is a Dutch-American biophysical chemist renowned for pioneering the use of multidimensional nuclear magnetic resonance (NMR) spectroscopy to study the structure and dynamics of biological macromolecules.
  • E. Baki
    Baki was a prominent 16th-century Ottoman Turkish poet renowned for his refined ghazals and mastery of classical divan literature.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: BTK
Triple: [Loxo Oncology, drugTarget, BTK]
Generated description
BTK (Bruton’s tyrosine kinase) is a key signaling enzyme in B cells and a major therapeutic target in certain blood cancers and autoimmune diseases.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: BTK
Target entity description: BTK (Bruton’s tyrosine kinase) is a key signaling enzyme in B cells and a major therapeutic target in certain blood cancers and autoimmune diseases.
  • A. Batta
    Batta is an ethnic group indigenous to northeastern Nigeria, particularly associated with Adamawa State.
  • B. Bt
    Bt is the post-nominal abbreviation for a baronetcy title in the British honours system, indicating that the holder is a baronet.
  • C. Batz
    Batz is a German surname most notably associated with World War II Luftwaffe fighter ace Wilhelm Batz.
  • D. Bax
    Bax is a Dutch-American biophysical chemist renowned for pioneering the use of multidimensional nuclear magnetic resonance (NMR) spectroscopy to study the structure and dynamics of biological macromolecules.
  • E. Baki
    Baki was a prominent 16th-century Ottoman Turkish poet renowned for his refined ghazals and mastery of classical divan literature.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69c00872444c8190bfaf1739dcec765c completed March 22, 2026, 3:19 p.m.
NER Named-entity recognition batch_69c04f0f63148190826198281dce3713 completed March 22, 2026, 8:20 p.m.
NED1 Entity disambiguation (via context triple) batch_69c1088f5c84819094e4696c24c4dd79 completed March 23, 2026, 9:31 a.m.
NEDg Description generation batch_69c1099f00f88190a5f1f0fafbb679c2 completed March 23, 2026, 9:36 a.m.
NED2 Entity disambiguation (via description) batch_69c10a2ffdcc8190bfeebc59d98b2b29 completed March 23, 2026, 9:38 a.m.
Created at: March 22, 2026, 4:06 p.m.