doseAdjustmentRequiredIn
P61679
predicate
Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.
All labels observed (6)
| Label | Occurrences |
|---|---|
| requiresDoseAdjustmentIn | 6 |
| doseAdjustmentRequiredIn canonical | 2 |
| mayRequireDoseModificationIn | 2 |
| doseAdjustment | 1 |
| requiresAdjustmentIn | 1 |
| requiresRegularDoseAdjustment | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: doseAdjustmentRequiredIn
Generated description
Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.
Sample triples (13)
| Subject | Object |
|---|---|
|
memantine
surface form:
Memantine
|
severe renal impairment ⓘ |
| Cymbalta | hepatic impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |
| amantadine | renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |
| Xeloda | renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |
| warfarin | true via predicate surface "requiresRegularDoseAdjustment" ⓘ |
| Januvia | renal impairment ⓘ |
| Lyrica | renal impairment via predicate surface "requiresAdjustmentIn" ⓘ |
| Ebixa | renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |
| ABVD regimen | renal impairment via predicate surface "mayRequireDoseModificationIn" ⓘ |
| ABVD regimen | hepatic impairment via predicate surface "mayRequireDoseModificationIn" ⓘ |
| FOLFIRI regimen | dose reduction may be required in patients with UGT1A1*28 polymorphism for irinotecan via predicate surface "doseAdjustment" ⓘ |
| DOAC | renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |
| DOAC | hepatic impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ |