doseAdjustmentRequiredIn

P61679
predicate

Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.

All labels observed (6)

Label Occurrences
requiresDoseAdjustmentIn 6
doseAdjustmentRequiredIn canonical 2
mayRequireDoseModificationIn 2

Description generation (PDg)

The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.

Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning.  
# Instructions
Focus on describing the relationship, not the entities themselves. 
# Response Format
Begin the description with \' Indicates...\'
Input
Predicate: doseAdjustmentRequiredIn
Generated description
Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.

Sample triples (13)

Subject Object
memantine
surface form: Memantine
severe renal impairment
Cymbalta hepatic impairment via predicate surface "requiresDoseAdjustmentIn"
amantadine renal impairment via predicate surface "requiresDoseAdjustmentIn"
Xeloda renal impairment via predicate surface "requiresDoseAdjustmentIn"
warfarin true via predicate surface "requiresRegularDoseAdjustment"
Januvia renal impairment
Lyrica renal impairment via predicate surface "requiresAdjustmentIn"
Ebixa renal impairment via predicate surface "requiresDoseAdjustmentIn"
ABVD regimen renal impairment via predicate surface "mayRequireDoseModificationIn"
ABVD regimen hepatic impairment via predicate surface "mayRequireDoseModificationIn"
FOLFIRI regimen dose reduction may be required in patients with UGT1A1*28 polymorphism for irinotecan via predicate surface "doseAdjustment"
DOAC renal impairment via predicate surface "requiresDoseAdjustmentIn"
DOAC hepatic impairment via predicate surface "requiresDoseAdjustmentIn"