ABVD regimen
E499490
The ABVD regimen is a standard chemotherapy combination used as first-line treatment for classical Hodgkin lymphoma.
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
chemotherapy regimen
ⓘ
combination chemotherapy ⓘ first-line treatment ⓘ |
| acronymFor |
Adriamycin
NERFINISHED
ⓘ
Bleomycin NERFINISHED ⓘ Dacarbazine NERFINISHED ⓘ Vinblastine ⓘ |
| comparedWith |
BEACOPP regimen
ⓘ
Stanford V regimen ⓘ |
| contraindicatedIn |
severe cardiac dysfunction
ⓘ
severe pulmonary dysfunction ⓘ |
| developedAs | alternative to MOPP regimen ⓘ |
| drugClassIncluded |
alkylating agent
ⓘ
anthracycline ⓘ antitumor antibiotic ⓘ vinca alkaloid ⓘ |
| guidelineRecommendedBy |
ASCO
NERFINISHED
ⓘ
ESMO NERFINISHED ⓘ NCCN NERFINISHED ⓘ |
| hasAdministrationSetting | outpatient oncology clinic ⓘ |
| hasComponentDrug |
adriamycin
NERFINISHED
ⓘ
bleomycin NERFINISHED ⓘ dacarbazine ⓘ doxorubicin ⓘ vinblastine ⓘ |
| hasRisk | infertility risk lower than MOPP ⓘ |
| hasToxicity |
alopecia
ⓘ
cardiotoxicity ⓘ myelosuppression ⓘ nausea and vomiting ⓘ peripheral neuropathy ⓘ pulmonary toxicity ⓘ |
| mayRequireDoseModificationIn |
hepatic impairment
ⓘ
renal impairment ⓘ |
| requiresMonitoringOf |
cardiac function
ⓘ
complete blood count ⓘ liver function tests ⓘ pulmonary function ⓘ renal function ⓘ |
| routeOfAdministration | intravenous ⓘ |
| standardOfCareFor | many newly diagnosed classical Hodgkin lymphoma patients ⓘ |
| treatmentIntent | curative ⓘ |
| typicalCycleLength | 28 days ⓘ |
| typicalNumberOfCycles | 2 to 6 cycles ⓘ |
| typicalSchedule | days 1 and 15 of a 28-day cycle ⓘ |
| usedFor |
Hodgkin lymphoma
NERFINISHED
ⓘ
classical Hodgkin lymphoma ⓘ |
| usedIn |
advanced-stage Hodgkin lymphoma
ⓘ
early-stage Hodgkin lymphoma ⓘ |
| usedInCombinationWith | involved-site radiotherapy ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.