Hodgkin lymphoma
E116434
Hodgkin lymphoma is a type of cancer that originates in the lymphatic system, characterized by the presence of abnormal Reed–Sternberg cells and often affecting lymph nodes.
All labels observed (8)
How this entity was disambiguated
This entity first appeared as the object of triple T979249 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Hodgkin lymphoma Context triple: [Mario Lemieux, diagnosedWith, Hodgkin lymphoma]
-
A.
Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
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B.
non-Hodgkin lymphoma
Non-Hodgkin lymphoma is a diverse group of blood cancers that originate in the lymphatic system from abnormal lymphocytes and can vary widely in aggressiveness and prognosis.
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C.
Virchow's node
Virchow's node is an enlarged left supraclavicular lymph node that classically indicates metastatic spread from abdominal or thoracic malignancies, especially gastric cancer.
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D.
SCLC
SCLC is a prominent American civil rights organization founded in 1957 that played a central role in the nonviolent struggle against racial segregation, led in part by Martin Luther King Jr.
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E.
SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Hodgkin lymphoma Target entity description: Hodgkin lymphoma is a type of cancer that originates in the lymphatic system, characterized by the presence of abnormal Reed–Sternberg cells and often affecting lymph nodes.
-
A.
Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
-
B.
non-Hodgkin lymphoma
Non-Hodgkin lymphoma is a diverse group of blood cancers that originate in the lymphatic system from abnormal lymphocytes and can vary widely in aggressiveness and prognosis.
-
C.
Virchow's node
Virchow's node is an enlarged left supraclavicular lymph node that classically indicates metastatic spread from abdominal or thoracic malignancies, especially gastric cancer.
-
D.
SCLC
SCLC is a prominent American civil rights organization founded in 1957 that played a central role in the nonviolent struggle against racial segregation, led in part by Martin Luther King Jr.
-
E.
SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
- F. None of above. chosen
Statements (54)
| Predicate | Object |
|---|---|
| instanceOf |
cancer
ⓘ
disease ⓘ hematologic malignancy ⓘ lymphoma ⓘ |
| affects | lymph nodes ⓘ |
| affectsSystem | lymphatic system ⓘ |
| characterizedBy |
Hodgkin lymphoma
self-linksurface differs
ⓘ
surface form:
Reed–Sternberg cells
|
| commonSymptom |
alcohol-induced lymph node pain
ⓘ
fatigue ⓘ fever ⓘ night sweats ⓘ painless lymphadenopathy ⓘ pruritus ⓘ unintentional weight loss ⓘ |
| firstDescribed | 1832 ⓘ |
| hasCellMarker |
CD15 positivity in classical Hodgkin lymphoma
ⓘ
CD20 positivity in nodular lymphocyte-predominant Hodgkin lymphoma ⓘ CD30 positivity in classical Hodgkin lymphoma ⓘ |
| hasComplication |
cardiovascular disease after mediastinal radiation
ⓘ
infertility after chemotherapy ⓘ secondary malignancies after treatment ⓘ |
| hasDiagnosticMethod |
PET-CT scan
ⓘ
excisional lymph node biopsy ⓘ histopathology ⓘ immunohistochemistry ⓘ |
| hasEpidemiologyFeature | bimodal age distribution ⓘ |
| hasMajorType |
classical Hodgkin lymphoma
ⓘ
Hodgkin lymphoma self-linksurface differs ⓘ
surface form:
nodular lymphocyte-predominant Hodgkin lymphoma
|
| hasPrognosticFactor |
age
ⓘ
disease stage ⓘ presence of B symptoms ⓘ serum LDH level ⓘ |
| hasRiskFactor |
Epstein–Barr virus infection
ⓘ
HIV infection ⓘ family history of lymphoma ⓘ immunosuppression ⓘ male sex ⓘ |
| hasSign | mediastinal mass ⓘ |
| hasSubtype |
Hodgkin lymphoma
self-linksurface differs
ⓘ
surface form:
lymphocyte-depleted classical Hodgkin lymphoma
Hodgkin lymphoma self-linksurface differs ⓘ
surface form:
lymphocyte-rich classical Hodgkin lymphoma
Hodgkin lymphoma self-linksurface differs ⓘ
surface form:
mixed cellularity classical Hodgkin lymphoma
Hodgkin lymphoma self-linksurface differs ⓘ
surface form:
nodular sclerosis classical Hodgkin lymphoma
|
| ICD10 | C81 ⓘ |
| namedAfter | Thomas Hodgkin ⓘ |
| prognosis | generally favorable with modern therapy ⓘ |
| stagedBy | Ann Arbor staging system ⓘ |
| treatedWith |
ABVD regimen
ⓘ
BEACOPP regimen ⓘ brentuximab vedotin ⓘ chemotherapy ⓘ immune checkpoint inhibitors ⓘ radiation therapy ⓘ |
| typicalAgeGroup |
older adults
ⓘ
young adults ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Hodgkin lymphoma Description of subject: Hodgkin lymphoma is a type of cancer that originates in the lymphatic system, characterized by the presence of abnormal Reed–Sternberg cells and often affecting lymph nodes.
Referenced by (19)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
Reed–Sternberg cells
this entity surface form:
nodular lymphocyte-predominant Hodgkin lymphoma
this entity surface form:
nodular sclerosis classical Hodgkin lymphoma
this entity surface form:
mixed cellularity classical Hodgkin lymphoma
this entity surface form:
lymphocyte-rich classical Hodgkin lymphoma
this entity surface form:
lymphocyte-depleted classical Hodgkin lymphoma
this entity surface form:
Hodgkin’s lymphoma