BEACOPP regimen
E499491
The BEACOPP regimen is an intensive multi-drug chemotherapy protocol used primarily for advanced-stage Hodgkin lymphoma.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
Hodgkin lymphoma treatment
ⓘ
chemotherapy regimen ⓘ combination chemotherapy protocol ⓘ |
| alsoKnownAs |
BEACOPP
NERFINISHED
ⓘ
escalated BEACOPP NERFINISHED ⓘ standard BEACOPP NERFINISHED ⓘ |
| comparedWith | ABVD regimen NERFINISHED ⓘ |
| componentDrug |
bleomycin
NERFINISHED
ⓘ
cyclophosphamide ⓘ doxorubicin ⓘ etoposide ⓘ prednisone ⓘ procarbazine NERFINISHED ⓘ vincristine ⓘ |
| contraindicationContext | often avoided in very elderly or frail patients due to toxicity ⓘ |
| cycleLength | 21 days ⓘ |
| developedFor | improving progression-free survival in advanced Hodgkin lymphoma ⓘ |
| drugClassOfComponent |
alkylating agents
ⓘ
anthracyclines ⓘ corticosteroids ⓘ topoisomerase II inhibitors ⓘ vinca alkaloids ⓘ |
| fullName | Bleomycin Etoposide Adriamycin Cyclophosphamide Oncovin Procarbazine Prednisone regimen NERFINISHED ⓘ |
| guidelineContext | considered in high-risk Hodgkin lymphoma in European guidelines ⓘ |
| hasVariant |
baseline BEACOPP
ⓘ
escalated-dose BEACOPP NERFINISHED ⓘ |
| indication |
advanced-stage Hodgkin lymphoma
ⓘ
high-risk Hodgkin lymphoma ⓘ unfavorable Hodgkin lymphoma ⓘ |
| namedAfter | initials of its component drugs ⓘ |
| requiresMonitoring |
blood counts
ⓘ
organ function ⓘ |
| routeOfAdministration |
intravenous
ⓘ
oral ⓘ |
| supportiveCareRequirement |
antiemetic prophylaxis
ⓘ
growth factor support in many protocols ⓘ |
| toxicity |
infection risk
ⓘ
infertility risk ⓘ myelosuppression ⓘ pulmonary toxicity ⓘ secondary malignancies risk ⓘ |
| treatmentGoal |
increase cure rate
ⓘ
reduce relapse risk ⓘ |
| treatmentSetting |
curative intent therapy
ⓘ
first-line therapy for advanced Hodgkin lymphoma ⓘ |
| typicalNumberOfCycles |
6
ⓘ
8 ⓘ |
| usedIn | combination with radiotherapy in some protocols ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.