Lyrica
E474930
Lyrica is a prescription medication (pregabalin) commonly used to treat nerve pain, fibromyalgia, and certain types of seizures.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
medication ⓘ |
| affectsSystem | central nervous system ⓘ |
| approvedBy | U.S. Food and Drug Administration NERFINISHED ⓘ |
| approvedIn |
European Union
NERFINISHED
ⓘ
United States NERFINISHED ⓘ |
| availableAs |
extended-release tablet
ⓘ
oral capsule ⓘ oral solution ⓘ |
| controlledSubstanceSchedule | Schedule V in the United States ⓘ |
| developedBy | Pfizer NERFINISHED ⓘ |
| FDAApprovalYear | 2005 ⓘ |
| firstApprovedRegion | European Union NERFINISHED ⓘ |
| firstApprovedYear | 2004 ⓘ |
| hasActiveIngredient | pregabalin NERFINISHED ⓘ |
| hasATCCode | N03AX16 ⓘ |
| hasBlackBoxWarning | risk of suicidal thoughts and behavior with antiepileptic drugs ⓘ |
| hasCommonSideEffect |
blurred vision
ⓘ
difficulty concentrating ⓘ dizziness ⓘ dry mouth ⓘ peripheral edema ⓘ somnolence ⓘ weight gain ⓘ |
| hasDrugClass |
anticonvulsant
ⓘ
antiepileptic drug ⓘ gabapentinoid ⓘ |
| hasEliminationHalfLife | about 6 hours in adults with normal renal function ⓘ |
| hasGenericName | pregabalin ⓘ |
| hasRisk |
dependence potential
ⓘ
misuse potential ⓘ withdrawal symptoms on abrupt discontinuation ⓘ |
| indicatedPopulation | adults ⓘ |
| isFormulationOf | pregabalin ⓘ |
| isNotRecommendedWith | concurrent alcohol use due to additive CNS depression ⓘ |
| legalStatus | prescription only ⓘ |
| mechanismOfAction | binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system ⓘ |
| pregnancyCategory | Category C (US, historical) ⓘ |
| primaryRouteOfElimination | renal ⓘ |
| requiresAdjustmentIn | renal impairment ⓘ |
| routeOfAdministration | oral ⓘ |
| treatsCondition |
diabetic peripheral neuropathy
ⓘ
fibromyalgia ⓘ focal seizures ⓘ neuropathic pain ⓘ neuropathic pain associated with spinal cord injury ⓘ partial-onset seizures ⓘ postherpetic neuralgia ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.