Ebixa
E494106
Ebixa is a brand-name medication containing memantine, used primarily to treat moderate to severe Alzheimer's disease.
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
brand-name medication
ⓘ
memantine-containing medicinal product ⓘ |
| actsOn | N-methyl-D-aspartate (NMDA) receptors ⓘ |
| administrationFrequency | once daily (maintenance dose) ⓘ |
| ATCCode | N06DX01 ⓘ |
| belongsTo | centrally acting anti-dementia drugs ⓘ |
| commonAdverseEffect |
confusion
ⓘ
constipation ⓘ dizziness ⓘ headache ⓘ hypertension ⓘ somnolence ⓘ |
| contraindication | hypersensitivity to memantine ⓘ |
| developedBy | H. Lundbeck A/S NERFINISHED ⓘ |
| dosageForm |
film-coated tablet
ⓘ
oral solution ⓘ |
| drugInteractionCaution |
amantadine
NERFINISHED
ⓘ
dextromethorphan NERFINISHED ⓘ ketamine NERFINISHED ⓘ other NMDA antagonists ⓘ |
| elimination | primarily renal excretion ⓘ |
| halfLife | about 60–80 hours ⓘ |
| hasActiveIngredient | memantine ⓘ |
| improves |
cognitive function in Alzheimer's disease
ⓘ
global functioning in Alzheimer's disease ⓘ |
| indication |
moderate Alzheimer's disease
ⓘ
severe Alzheimer's disease ⓘ |
| isBrandOf | memantine hydrochloride ⓘ |
| marketingAuthorizationHolder | Lundbeck NERFINISHED ⓘ |
| marketingAuthorizationRegion | European Union NERFINISHED ⓘ |
| maximumDailyDose | 20 mg memantine (typical in adults) ⓘ |
| maySlow | clinical deterioration in Alzheimer's disease ⓘ |
| metabolism | minimally metabolized in the liver ⓘ |
| notIndicatedFor | mild Alzheimer's disease ⓘ |
| pharmacologicalClass | NMDA receptor antagonist ⓘ |
| regulates | glutamatergic neurotransmission ⓘ |
| requires | prescription ⓘ |
| requiresCautionIn | severe renal impairment ⓘ |
| requiresDoseAdjustmentIn | renal impairment ⓘ |
| routeOfAdministration | oral ⓘ |
| targetPopulation |
adult patients
ⓘ
elderly patients ⓘ |
| therapeuticArea |
geriatrics
ⓘ
neurology ⓘ |
| titration | requires gradual dose escalation ⓘ |
| treats | Alzheimer's disease NERFINISHED ⓘ |
| usedIn | symptomatic treatment of Alzheimer's disease ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Memantine