Mycobacterium tuberculosis
E52537
Mycobacterium tuberculosis is the pathogenic bacterial species that causes most cases of human tuberculosis, primarily affecting the lungs and spreading through airborne transmission.
Statements (54)
| Predicate | Object |
|---|---|
| instanceOf |
bacterial species
→
pathogenic bacterium → |
| antibioticResistanceIssue |
extensively drug-resistant tuberculosis
→
multidrug-resistant tuberculosis → |
| antibioticTreatment |
ethambutol
→
isoniazid → pyrazinamide → rifampicin → |
| biosafetyLevel |
BSL-3
→
|
| capsule |
non-encapsulated
→
|
| cellWallComponent |
arabinogalactan
→
mycolic acids → peptidoglycan → |
| cultureMedium |
Lowenstein–Jensen medium
→
Middlebrook 7H10 agar → Middlebrook 7H9 broth → |
| discoveredBy |
Robert Koch
→
|
| discoveryYear |
1882
→
|
| diseaseInHumans |
extrapulmonary tuberculosis
→
pulmonary tuberculosis → |
| domain |
Bacteria
→
|
| family |
Mycobacteriaceae
→
|
| GCContent |
high GC content
→
|
| generationTime |
approximately 18–24 hours
→
|
| genomeSize |
approximately 4.4 megabases
→
|
| genomeType |
circular double-stranded DNA
→
|
| genus |
Mycobacterium
→
|
| gramStain |
acid-fast
→
|
| growthRate |
slow-growing
→
|
| host |
humans
→
other mammals → |
| immuneEvasionMechanism |
inhibition of phagosome–lysosome fusion
→
survival in macrophages → |
| metabolism |
aerobic respiration
→
|
| motility |
non-motile
→
|
| order |
Corynebacteriales
→
|
| oxygenRequirement |
obligate aerobe
→
|
| phylum |
Actinobacteria
→
|
| primaryDisease |
tuberculosis
→
|
| primaryTargetOrgan |
lungs
→
|
| relatedDiseaseComplex |
Mycobacterium tuberculosis complex
→
|
| shape |
rod-shaped
→
|
| sporeFormation |
non-spore-forming
→
|
| stainMethod |
Auramine–rhodamine stain
→
Ziehl–Neelsen stain → |
| taxonRank |
species
→
|
| transmissionRoute |
aerosol inhalation
→
airborne droplets → |
| vaccineTarget |
BCG vaccine
→
|
| virulenceFactor |
ESX-1 secretion system
→
cell wall lipids → cord factor (trehalose dimycolate) → phthiocerol dimycocerosates → |
| zoonoticPotential |
can infect animals
→
|
Referenced by (1)
| Subject (surface form when different) | Predicate |
|---|---|
|
Robert Koch
→
|
discovered |