receptor tyrosine kinase
C29137
concept
A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
All labels observed (5)
| Label | Occurrences |
|---|---|
| receptor tyrosine kinase canonical | 6 |
| ErbB family member | 1 |
| ErbB receptor family member | 1 |
| growth factor receptor family | 1 |
| receptor tyrosine kinase family | 1 |
Description generation (CDg)
The one-sentence description above was generated by prompting gpt-5.1 with the class name and this instruction.
Instruction
generate a one-sentence description for a given conceptual class. # Response Format Return only the sentence: "Description: [one-sentence description of the conceptional class]"
Input
Class: receptor tyrosine kinase
Generated description
A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
Instances (7)
| Instance | Via concept surface |
|---|---|
| HER2 receptor | — |
| ERBB2 | — |
| CD340 | — |
| EGFR | — |
| ERBB3 | — |
| epidermal growth factor receptor family | receptor tyrosine kinase family |
| ERBB4 | — |