Ebola virus disease
E85058
Ebola virus disease is a severe, often fatal illness in humans caused by infection with Ebola virus, characterized by fever, hemorrhaging, and organ failure, and known for causing major outbreaks such as the 2014–2016 West Africa epidemic.
Statements (70)
| Predicate | Object |
|---|---|
| instanceOf |
infectious disease
→
viral hemorrhagic fever → zoonotic disease → |
| affectedCountries |
Democratic Republic of the Congo
→
Guinea NERFINISHED → Liberia → Sierra Leone → Uganda → |
| biosafetyLevel |
BSL-4 pathogen
→
|
| caseFatalityRate |
often between 25% and 90%
→
|
| causativeAgent |
Bombali ebolavirus
→
Bundibugyo ebolavirus → Ebolavirus → Reston ebolavirus → Sudan ebolavirus → Taï Forest ebolavirus → Zaire ebolavirus → |
| cause |
fever
→
hemorrhaging → high case fatality rate → organ failure → severe illness in humans → |
| diagnosis |
ELISA antibody tests
→
PCR testing → antigen-capture detection tests → |
| firstDescribed |
1976
→
|
| firstOutbreakLocation |
Nzara, Sudan
→
Yambuku, Zaire → |
| hasComplication |
death
→
multi-organ failure → shock → |
| ICD10 |
A98.4
→
|
| majorOutbreak |
1995 Kikwit outbreak
→
2000–2001 Uganda outbreak → 2014–2016 West Africa Ebola outbreak → 2018–2020 Kivu Ebola epidemic → |
| namedAfter |
Ebola River
→
|
| prevention |
avoidance of contact with infected animals
→
community engagement → infection prevention and control measures in healthcare settings → safe burial practices → |
| probableReservoir |
fruit bats
→
|
| recognizedBy |
Centers for Disease Control and Prevention
→
World Health Organization → |
| riskGroup |
family members of infected persons
→
funeral participants → healthcare workers → |
| symptom |
diarrhea
→
external bleeding → headache → impaired kidney function → impaired liver function → internal bleeding → muscle pain → rash → severe weakness → sore throat → sudden onset of fever → vomiting → |
| transmission |
human-to-human transmission via direct contact with blood
→
human-to-human transmission via direct contact with body fluids → not transmitted by airborne route under usual conditions → transmission via contaminated surfaces → transmission via infected animals → |
| treatment |
monoclonal antibody therapies
→
rehydration with oral or intravenous fluids → supportive care → treatment of specific symptoms → |
| vaccine |
Ervebo
→
rVSV-ZEBOV → |
Referenced by (5)
| Subject (surface form when different) | Predicate |
|---|---|
|
2014–2016 West Africa Ebola outbreak
→
2018–2020 Kivu Ebola epidemic in the Democratic Republic of the Congo → |
disease |
|
Meliandou
→
|
associatedDisease |
|
Zaire ebolavirus
→
|
causesDisease |
|
UNMEER
→
|
focusesOn |