Zaire ebolavirus

E86056

Ebolavirus filovirus virus species

Zaire ebolavirus is a highly virulent species of Ebola virus responsible for severe hemorrhagic fever outbreaks in humans, including the major 2014–2016 epidemic in West Africa.

Aliases (2)

EBOV ×1
Ebola virus Zaire strain ×1

Statements (50)

Predicate	Object
instanceOf	Ebolavirus → filovirus → virus species →
abbreviation	EBOV →
approvedVaccine	rVSV-ZEBOV →
associatedOutbreak	1976 Ebola outbreak in Zaire → 1995 Kikwit Ebola outbreak → 2007 Ebola outbreak in Democratic Republic of the Congo → 2014–2016 West Africa Ebola outbreak → 2018–2020 Kivu Ebola outbreak → 2021 Ebola outbreak in Guinea →
biosafetyLevel	BSL-4 →
caseFatalityRateRange	25–90 percent →
causesDisease	Ebola virus disease → viral hemorrhagic fever →
enveloped	true →
family	Filoviridae →
firstIdentifiedCountryCurrentName	Democratic Republic of the Congo →
firstIdentifiedIn	1976 →
firstIdentifiedLocation	Yambuku, Zaire →
genomeSegmentCount	1 →
genomeStructure	non-segmented →
genomeType	negative-sense single-stranded RNA →
genus	Ebolavirus →
hasVaccine	true →
host	human → non-human primate →
naturalReservoir	fruit bat →
notableEpidemicRegion	Democratic Republic of the Congo → Gabon NERFINISHED → Guinea NERFINISHED → Liberia → Republic of the Congo → Sierra Leone →
order	Mononegavirales →
parentTaxon	Ebolavirus →
pathogenicityInHumans	severe →
primaryTropism	dendritic cells → endothelial cells → monocytes and macrophages →
realm	Riboviria →
shape	filamentous →
taxonRank	species →
transmissionBetweenHumans	true →
transmissionRoute	direct contact with blood → direct contact with body fluids → direct contact with contaminated materials →
virulence	high →
WHOPriorityPathogen	true →
zoonotic	true →

Referenced by (6)

Subject (surface form when different)	Predicate
2014–2016 West Africa Ebola outbreak → Ebola virus disease →	causativeAgent
Zaire ebolavirus ("EBOV") →	abbreviation
rVSV-ZEBOV →	targetPathogen
rVSV-ZEBOV ("Ebola virus Zaire strain") →	targetStrain
2018–2020 Kivu Ebola epidemic in the Democratic Republic of the Congo →	virus