Dobzhansky–Muller incompatibilities
E725886
Dobzhansky–Muller incompatibilities are genetic conflicts between interacting genes that evolve in separate populations, causing reduced fitness or sterility in their hybrids and thereby contributing to reproductive isolation and speciation.
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
genetic incompatibility model
ⓘ
reproductive isolation mechanism ⓘ speciation mechanism ⓘ |
| appliesTo |
mitochondrial–nuclear interactions
ⓘ
nuclear genes ⓘ sex chromosome–autosome interactions ⓘ |
| assumes | allopatric divergence of populations ⓘ |
| basedOn |
epistasis
ⓘ
fixation of different alleles in isolated populations ⓘ |
| contrastsWith | single-locus underdominance models of isolation ⓘ |
| contributesTo |
genetic barriers to gene flow
ⓘ
speciation ⓘ |
| describes |
genetic conflicts between interacting loci fixed in different populations
ⓘ
hybrid inviability ⓘ hybrid sterility ⓘ postzygotic reproductive isolation ⓘ |
| emergesWhen | hybrid combines incompatible derived alleles ⓘ |
| explains |
evolution of intrinsic postzygotic isolation
ⓘ
how hybrid problems can evolve without reduced fitness in parental populations ⓘ |
| field |
evolutionary biology
ⓘ
population genetics ⓘ speciation genetics ⓘ |
| hasCause | epistatic interactions between derived alleles from different populations ⓘ |
| hasComponent |
derived allele in population 1
ⓘ
derived allele in population 2 ⓘ |
| hasEffect |
hybrid inviability
ⓘ
hybrid sterility ⓘ postzygotic reproductive isolation between populations ⓘ reduced hybrid fitness ⓘ |
| interactionType | negative epistasis ⓘ |
| namedAfter |
Hermann Joseph Muller
NERFINISHED
ⓘ
Theodosius Dobzhansky NERFINISHED ⓘ |
| predicts |
incompatibilities can accumulate faster than linearly with divergence
ⓘ
multiple loci contribute to reproductive isolation ⓘ |
| relatedConcept | Bateson–Dobzhansky–Muller model NERFINISHED ⓘ |
| relatedTo |
Haldane's rule
NERFINISHED
ⓘ
genetic architecture of speciation ⓘ |
| supports | biological species concept ⓘ |
| testedIn |
Drosophila
NERFINISHED
ⓘ
mammals ⓘ plants ⓘ yeast ⓘ |
| timeScale | can accumulate gradually over evolutionary time ⓘ |
| usedIn |
genome scan studies of reproductive barriers
ⓘ
quantitative genetic studies of hybrid fitness ⓘ theoretical models of speciation ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.