Haldane’s rule
E194834
Haldane’s rule is a principle in evolutionary biology stating that when in the offspring of two different animal species or subspecies one sex is absent, rare, or sterile, that sex is usually the heterogametic one (e.g., XY or ZW).
All labels observed (1)
| Label | Occurrences |
|---|---|
| Haldane’s rule canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T1726032 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
Target entity: Haldane’s rule Context triple: [J. B. S. Haldane, notableFor, Haldane’s rule]
-
A.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
-
B.
Law for the Prevention of Hereditarily Diseased Offspring
The Law for the Prevention of Hereditarily Diseased Offspring was a 1933 Nazi eugenics statute that mandated the forced sterilization of hundreds of thousands of people deemed genetically "unfit," including those with disabilities and certain illnesses.
-
C.
Genetics and the Origin of Species
Genetics and the Origin of Species is a 1937 book by Theodosius Dobzhansky that helped found the modern evolutionary synthesis by integrating Mendelian genetics with Darwinian natural selection.
-
D.
Kettlewell
Kettlewell is a central character in the novel "Makers" by Cory Doctorow, known as an idealistic inventor navigating the disruptive world of post-scarcity technology and maker culture.
-
E.
The Effects of Cross and Self Fertilisation in the Vegetable Kingdom
"The Effects of Cross and Self Fertilisation in the Vegetable Kingdom" is a scientific book by Charles Darwin that experimentally investigates how cross-fertilisation and self-fertilisation influence the vigor, fertility, and evolution of plants.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
Target entity: Haldane’s rule Target entity description: Haldane’s rule is a principle in evolutionary biology stating that when in the offspring of two different animal species or subspecies one sex is absent, rare, or sterile, that sex is usually the heterogametic one (e.g., XY or ZW).
-
A.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
-
B.
Law for the Prevention of Hereditarily Diseased Offspring
The Law for the Prevention of Hereditarily Diseased Offspring was a 1933 Nazi eugenics statute that mandated the forced sterilization of hundreds of thousands of people deemed genetically "unfit," including those with disabilities and certain illnesses.
-
C.
Genetics and the Origin of Species
Genetics and the Origin of Species is a 1937 book by Theodosius Dobzhansky that helped found the modern evolutionary synthesis by integrating Mendelian genetics with Darwinian natural selection.
-
D.
Kettlewell
Kettlewell is a central character in the novel "Makers" by Cory Doctorow, known as an idealistic inventor navigating the disruptive world of post-scarcity technology and maker culture.
-
E.
The Effects of Cross and Self Fertilisation in the Vegetable Kingdom
"The Effects of Cross and Self Fertilisation in the Vegetable Kingdom" is a scientific book by Charles Darwin that experimentally investigates how cross-fertilisation and self-fertilisation influence the vigor, fertility, and evolution of plants.
- F. None of above. chosen
Statements (44)
| Predicate | Object |
|---|---|
| instanceOf |
evolutionary biology principle
ⓘ
rule in speciation genetics ⓘ |
| appliesTo |
animals with genetic sex determination
ⓘ
hybrids between species ⓘ hybrids between subspecies ⓘ |
| appliesWhen |
one hybrid sex is absent
ⓘ
one hybrid sex is rare ⓘ one hybrid sex is sterile ⓘ |
| concerns |
hybrid inviability
ⓘ
hybrid sterility ⓘ sex-specific hybrid dysfunction ⓘ |
| exceptionCases |
taxa with environmental sex determination
ⓘ
taxa without differentiated sex chromosomes ⓘ |
| explainedBy |
dominance theory of hybrid incompatibilities
ⓘ
faster-X theory ⓘ faster-male theory ⓘ |
| field |
evolutionary biology
ⓘ
hybridization studies ⓘ speciation research ⓘ |
| heterogameticSexExamples |
XY males in mammals and Drosophila
ⓘ
ZW females in birds and butterflies ⓘ |
| involves |
heterogametic sex
ⓘ
homogametic sex ⓘ sex-linked genetic incompatibilities ⓘ |
| namedAfter | J. B. S. Haldane ⓘ |
| originallyFormulatedBy | J. B. S. Haldane ⓘ |
| originalPublicationContext | paper on hybrid sterility in the journal Journal of Genetics ⓘ |
| originalPublicationYear | 1922 ⓘ |
| patternType | empirical generalization ⓘ |
| predicts |
greater hybrid inviability in the heterogametic sex
ⓘ
greater hybrid sterility in the heterogametic sex ⓘ |
| relatedConcept |
Dobzhansky–Muller incompatibilities
ⓘ
postzygotic reproductive isolation ⓘ sex chromosomes ⓘ speciation genetics ⓘ |
| states | the heterogametic sex is more likely to be absent, rare, or sterile in hybrids ⓘ |
| status | widely accepted empirical rule in evolutionary biology ⓘ |
| supportedBy |
data from Drosophila hybrids
ⓘ
data from Lepidoptera hybrids ⓘ data from avian hybrids ⓘ data from mammalian hybrids ⓘ |
| usedIn |
comparative analyses of reproductive isolation
ⓘ
interpretation of hybrid zone patterns ⓘ tests of speciation models ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Subject: Haldane’s rule Description of subject: Haldane’s rule is a principle in evolutionary biology stating that when in the offspring of two different animal species or subspecies one sex is absent, rare, or sterile, that sex is usually the heterogametic one (e.g., XY or ZW).
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.