TAF15
E561107
TAF15 is an RNA-binding protein and transcription factor associated with gene regulation and implicated in certain cancers and neurodegenerative diseases.
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
RNA-binding protein
ⓘ
gene regulatory protein ⓘ protein ⓘ transcription factor ⓘ |
| aggregationLinkedTo | neurodegeneration ⓘ |
| alsoKnownAs |
RBP56
ⓘ
TAFII68 NERFINISHED ⓘ |
| associatedWith |
acute leukemia
ⓘ
amyotrophic lateral sclerosis ⓘ cancer ⓘ frontotemporal dementia ⓘ neurodegenerative disease ⓘ sarcoma ⓘ |
| bindsMolecule |
DNA
ⓘ
RNA ⓘ single-stranded RNA ⓘ |
| canAggregate | yes ⓘ |
| conservedIn | vertebrates ⓘ |
| encodedBy | TAF15 gene NERFINISHED ⓘ |
| formsFusionWith |
CIZ/NMP4
ⓘ
EWSR1-related partners ⓘ MLL NERFINISHED ⓘ NR4A3 NERFINISHED ⓘ |
| fullName | TATA-box binding protein associated factor 15 NERFINISHED ⓘ |
| hasDomain |
RGG-rich region
ⓘ
RNA recognition motif ⓘ low-complexity prion-like domain ⓘ |
| hasMolecularFunction |
DNA binding
ⓘ
RNA binding ⓘ RNA splicing factor activity ⓘ transcription coactivator activity ⓘ |
| implicatedIn |
aberrant RNA metabolism
ⓘ
aberrant transcriptional activation ⓘ oncogenic gene fusions ⓘ |
| interactsWith |
RNA polymerase II transcription machinery
ⓘ
TATA-binding protein associated factors NERFINISHED ⓘ |
| locatedIn |
cytoplasm
ⓘ
nucleus ⓘ |
| memberOf | FET protein family NERFINISHED ⓘ |
| orthologIn | Homo sapiens NERFINISHED ⓘ |
| participatesIn |
RNA processing
ⓘ
gene expression regulation ⓘ mRNA splicing ⓘ mRNA stability regulation ⓘ transcription regulation ⓘ |
| postTranslationalModification |
arginine methylation
ⓘ
phosphorylation ⓘ |
| subcellularLocalization |
nuclear speckles
ⓘ
stress granules ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.