THC
E55576
THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis responsible for the plant’s mind-altering effects.
All labels observed (3)
| Label | Occurrences |
|---|---|
| THC canonical | 5 |
| delta-9-THC | 1 |
| Δ⁹-THC | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T442798 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: THC Context triple: [Cannabis, producesCompound, THC]
-
A.
Cannabis
Cannabis is a genus of flowering plants best known for producing psychoactive and medicinal compounds such as THC and CBD, widely used for recreational, therapeutic, and industrial (hemp) purposes.
-
B.
Canna
Canna is a small, historically rich island in Scotland’s Inner Hebrides, known for its wildlife, archaeological sites, and ownership by the National Trust for Scotland.
-
C.
CBG
CBG is the National Rail station code for Cambridge railway station in Cambridge, England.
-
D.
Papaver somniferum
Papaver somniferum is the opium poppy, a flowering plant cultivated both for its edible seeds and for producing opiates such as morphine and codeine.
-
E.
Cresco
Cresco is a small city in northeastern Iowa known for its agricultural community and historic architecture.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: THC Target entity description: THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis responsible for the plant’s mind-altering effects.
-
A.
Cannabis
Cannabis is a genus of flowering plants best known for producing psychoactive and medicinal compounds such as THC and CBD, widely used for recreational, therapeutic, and industrial (hemp) purposes.
-
B.
Canna
Canna is a small, historically rich island in Scotland’s Inner Hebrides, known for its wildlife, archaeological sites, and ownership by the National Trust for Scotland.
-
C.
CBG
CBG is the National Rail station code for Cambridge railway station in Cambridge, England.
-
D.
Papaver somniferum
Papaver somniferum is the opium poppy, a flowering plant cultivated both for its edible seeds and for producing opiates such as morphine and codeine.
-
E.
Cresco
Cresco is a small city in northeastern Iowa known for its agricultural community and historic architecture.
- F. None of above. chosen
Statements (70)
| Predicate | Object |
|---|---|
| instanceOf |
organic compound
ⓘ
phytocannabinoid ⓘ psychoactive drug ⓘ terpenophenolic compound ⓘ |
| actsOnReceptor |
CB1 receptor
ⓘ
CB2 receptor ⓘ |
| administrationRoute |
inhalation
ⓘ
oral ⓘ sublingual ⓘ topical ⓘ |
| alsoKnownAs |
THC
ⓘ
surface form:
delta-9-THC
delta-9-tetrahydrocannabinol ⓘ THC ⓘ
surface form:
Δ⁹-THC
|
| biosynthesizedFrom | THCA (tetrahydrocannabinolic acid) ⓘ |
| boilingPoint | 157 °C ⓘ |
| canCause | acute cognitive impairment ⓘ |
| chemicalFormula | C21H30O2 ⓘ |
| chemicalName | tetrahydrocannabinol ⓘ |
| conversionProcess | decarboxylation of THCA ⓘ |
| dependencePotential | can lead to cannabis use disorder in some users ⓘ |
| detectableIn |
blood
ⓘ
hair ⓘ saliva ⓘ urine ⓘ |
| discoveredIn | 20th century ⓘ |
| drugClass | cannabinoid receptor agonist ⓘ |
| durationInhalation | 2–4 hours ⓘ |
| durationOral | 4–8 hours ⓘ |
| excretionRoute |
feces
ⓘ
urine ⓘ |
| foundIn |
Cannabis
ⓘ
surface form:
Cannabis indica
Cannabis ⓘ
surface form:
Cannabis sativa
|
| isolatedBy | Raphael Mechoulam ⓘ |
| IUPACName | (−)-trans-Δ⁹-tetrahydrocannabinol ⓘ |
| legalStatus | controlled substance in many countries ⓘ |
| legalUse |
medical use in some jurisdictions
ⓘ
recreational use in some jurisdictions ⓘ |
| meltingPoint | 66 °C ⓘ |
| metabolizedIn | liver ⓘ |
| molarMass | 314.46 g/mol ⓘ |
| onsetInhalation | within minutes ⓘ |
| onsetOral | 30–120 minutes ⓘ |
| origin | plant-derived ⓘ |
| potentialTherapeuticUse |
analgesic
ⓘ
antiemetic ⓘ appetite stimulant ⓘ |
| primaryMetabolite | 11-hydroxy-THC ⓘ |
| psychoactiveEffect |
altered perception
ⓘ
altered time perception ⓘ euphoria ⓘ impairment of short-term memory ⓘ increased appetite ⓘ relaxation ⓘ |
| receptorSystem | endocannabinoid system ⓘ |
| relatedCompound |
CBD (cannabidiol)
ⓘ
CBN (cannabinol) ⓘ |
| role | primary psychoactive constituent of cannabis ⓘ |
| scheduleUS | Schedule I controlled substance at federal level (except certain formulations) ⓘ |
| secondaryMetabolite | THC-COOH ⓘ |
| sideEffect |
anxiety
ⓘ
dry mouth ⓘ impaired coordination ⓘ paranoia ⓘ red eyes ⓘ tachycardia ⓘ |
| solubility |
insoluble in water
ⓘ
soluble in lipids ⓘ soluble in organic solvents ⓘ |
| usedIn | prescription medicine dronabinol (synthetic THC) ⓘ |
| yearIsolated | 1964 ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: THC Description of subject: THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis responsible for the plant’s mind-altering effects.
Referenced by (7)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
Δ⁹-THC
this entity surface form:
delta-9-THC
subject surface form:
THCA
subject surface form:
THCA
subject surface form:
THCA