THC
E55576
THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis responsible for the plant’s mind-altering effects.
Observed surface forms (2)
| Surface form | Occurrences |
|---|---|
| delta-9-THC | 1 |
| Δ⁹-THC | 1 |
Statements (70)
| Predicate | Object |
|---|---|
| instanceOf |
organic compound
ⓘ
phytocannabinoid ⓘ psychoactive drug ⓘ terpenophenolic compound ⓘ |
| actsOnReceptor |
CB1 receptor
ⓘ
CB2 receptor ⓘ |
| administrationRoute |
inhalation
ⓘ
oral ⓘ sublingual ⓘ topical ⓘ |
| alsoKnownAs |
THC
ⓘ
surface form:
delta-9-THC
delta-9-tetrahydrocannabinol ⓘ THC ⓘ
surface form:
Δ⁹-THC
|
| biosynthesizedFrom | THCA (tetrahydrocannabinolic acid) ⓘ |
| boilingPoint | 157 °C ⓘ |
| canCause | acute cognitive impairment ⓘ |
| chemicalFormula | C21H30O2 ⓘ |
| chemicalName | tetrahydrocannabinol ⓘ |
| conversionProcess | decarboxylation of THCA ⓘ |
| dependencePotential | can lead to cannabis use disorder in some users ⓘ |
| detectableIn |
blood
ⓘ
hair ⓘ saliva ⓘ urine ⓘ |
| discoveredIn | 20th century ⓘ |
| drugClass | cannabinoid receptor agonist ⓘ |
| durationInhalation | 2–4 hours ⓘ |
| durationOral | 4–8 hours ⓘ |
| excretionRoute |
feces
ⓘ
urine ⓘ |
| foundIn |
Cannabis
ⓘ
surface form:
Cannabis indica
Cannabis ⓘ
surface form:
Cannabis sativa
|
| isolatedBy | Raphael Mechoulam ⓘ |
| IUPACName | (−)-trans-Δ⁹-tetrahydrocannabinol ⓘ |
| legalStatus | controlled substance in many countries ⓘ |
| legalUse |
medical use in some jurisdictions
ⓘ
recreational use in some jurisdictions ⓘ |
| meltingPoint | 66 °C ⓘ |
| metabolizedIn | liver ⓘ |
| molarMass | 314.46 g/mol ⓘ |
| onsetInhalation | within minutes ⓘ |
| onsetOral | 30–120 minutes ⓘ |
| origin | plant-derived ⓘ |
| potentialTherapeuticUse |
analgesic
ⓘ
antiemetic ⓘ appetite stimulant ⓘ |
| primaryMetabolite | 11-hydroxy-THC ⓘ |
| psychoactiveEffect |
altered perception
ⓘ
altered time perception ⓘ euphoria ⓘ impairment of short-term memory ⓘ increased appetite ⓘ relaxation ⓘ |
| receptorSystem | endocannabinoid system ⓘ |
| relatedCompound |
CBD (cannabidiol)
ⓘ
CBN (cannabinol) ⓘ |
| role | primary psychoactive constituent of cannabis ⓘ |
| scheduleUS | Schedule I controlled substance at federal level (except certain formulations) ⓘ |
| secondaryMetabolite | THC-COOH ⓘ |
| sideEffect |
anxiety
ⓘ
dry mouth ⓘ impaired coordination ⓘ paranoia ⓘ red eyes ⓘ tachycardia ⓘ |
| solubility |
insoluble in water
ⓘ
soluble in lipids ⓘ soluble in organic solvents ⓘ |
| usedIn | prescription medicine dronabinol (synthetic THC) ⓘ |
| yearIsolated | 1964 ⓘ |
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
Δ⁹-THC
this entity surface form:
delta-9-THC