Zika virus
E419028
Zika virus is a mosquito-borne flavivirus that can cause mild illness in adults but is strongly associated with severe birth defects such as microcephaly when contracted during pregnancy.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Zika virus canonical | 6 |
| Zika fever | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4200511 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Zika virus Context triple: [2015–2016 Zika virus outbreak, mainCause, Zika virus]
-
A.
2015–2016 Zika virus outbreak
The 2015–2016 Zika virus outbreak was a major global health crisis, centered in the Americas, marked by mosquito-borne transmission and severe birth defects such as microcephaly, prompting international public health emergencies and coordinated responses.
-
B.
Zaire ebolavirus
Zaire ebolavirus is a highly virulent species of Ebola virus responsible for severe hemorrhagic fever outbreaks in humans, including the major 2014–2016 epidemic in West Africa.
-
C.
Ebolavirus
Ebolavirus is a genus of filamentous, enveloped RNA viruses in the Filoviridae family that cause severe and often fatal hemorrhagic fever in humans and other primates.
-
D.
Chengue
Chengue is an archaeological site in Colombia associated with the pre-Columbian Tairona culture, known for its stone terraces and evidence of complex indigenous settlement.
-
E.
Ebola virus disease
Ebola virus disease is a severe, often fatal illness in humans caused by infection with Ebola virus, characterized by fever, hemorrhaging, and organ failure, and known for causing major outbreaks such as the 2014–2016 West Africa epidemic.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Zika virus Target entity description: Zika virus is a mosquito-borne flavivirus that can cause mild illness in adults but is strongly associated with severe birth defects such as microcephaly when contracted during pregnancy.
-
A.
2015–2016 Zika virus outbreak
The 2015–2016 Zika virus outbreak was a major global health crisis, centered in the Americas, marked by mosquito-borne transmission and severe birth defects such as microcephaly, prompting international public health emergencies and coordinated responses.
-
B.
Zaire ebolavirus
Zaire ebolavirus is a highly virulent species of Ebola virus responsible for severe hemorrhagic fever outbreaks in humans, including the major 2014–2016 epidemic in West Africa.
-
C.
Ebolavirus
Ebolavirus is a genus of filamentous, enveloped RNA viruses in the Filoviridae family that cause severe and often fatal hemorrhagic fever in humans and other primates.
-
D.
Chengue
Chengue is an archaeological site in Colombia associated with the pre-Columbian Tairona culture, known for its stone terraces and evidence of complex indigenous settlement.
-
E.
Ebola virus disease
Ebola virus disease is a severe, often fatal illness in humans caused by infection with Ebola virus, characterized by fever, hemorrhaging, and organ failure, and known for causing major outbreaks such as the 2014–2016 West Africa epidemic.
- F. None of above. chosen
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
arbovirus
ⓘ
flavivirus ⓘ virus ⓘ |
| associatedCondition |
Guillain–Barré syndrome
ⓘ
microcephaly ⓘ |
| associatedDisease |
Zika virus
self-linksurface differs
ⓘ
surface form:
Zika fever
congenital Zika syndrome ⓘ |
| biosafetyLevel | BSL-2 ⓘ |
| diagnosticMethod |
RT-PCR
ⓘ
serology ⓘ |
| effectWhenInfectionDuringPregnancy |
congenital microcephaly
ⓘ
fetal brain abnormalities ⓘ pregnancy loss ⓘ |
| enveloped | true ⓘ |
| family | Flaviviridae ⓘ |
| firstHostIsolatedFrom | rhesus macaque ⓘ |
| firstHumanCaseReportYear | 1952 ⓘ |
| firstIsolationPlace | Zika Forest, Uganda ⓘ |
| firstIsolationYear | 1947 ⓘ |
| genomePolarity | +ssRNA ⓘ |
| genomeType | single-stranded RNA ⓘ |
| host |
human
ⓘ
non-human primate ⓘ |
| infectionSeverityInAdults | usually mild ⓘ |
| notableOutbreak |
Americas outbreak 2015–2016
ⓘ
French Polynesia outbreak 2013–2014 ⓘ Yap Island outbreak 2007 ⓘ |
| parentTaxon | Flavivirus ⓘ |
| preventiveMeasure |
avoiding travel to affected areas during pregnancy
ⓘ
insect repellent use ⓘ mosquito control ⓘ mosquito nets ⓘ |
| primaryTropism | neural progenitor cells ⓘ |
| riskGroup | pregnant women ⓘ |
| symptomInAdults |
arthralgia
ⓘ
conjunctivitis ⓘ fever ⓘ headache ⓘ myalgia ⓘ rash ⓘ |
| taxonRank | species ⓘ |
| transmissionRoute |
blood transfusion
ⓘ
mosquito bite ⓘ sexual transmission ⓘ vertical transmission ⓘ |
| transmissionVector |
Aedes aegypti mosquito
ⓘ
Aedes albopictus mosquito ⓘ |
| treatmentType | supportive care ⓘ |
| vaccineAvailable | false ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Zika virus Description of subject: Zika virus is a mosquito-borne flavivirus that can cause mild illness in adults but is strongly associated with severe birth defects such as microcephaly when contracted during pregnancy.
Referenced by (7)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
human adenovirus serotype 26
this entity surface form:
Zika fever
subject surface form:
Aedes aegypti