Ambien

E411218

Ambien is a widely prescribed sedative-hypnotic medication (generic name zolpidem) used short-term to treat insomnia by helping people fall asleep more quickly.

All labels observed (3)

Label Occurrences
Ambien canonical 1
Ambien CR 1
zolpidem 1

How this entity was disambiguated

Statements (48)

Predicate Object
instanceOf brand name drug
medication
sedative-hypnotic drug
actsOn GABA-A receptor
administrationInstruction should be taken immediately before bedtime
should be taken only when able to stay in bed for a full night
boxedWarningUS complex sleep behaviors resulting in serious injuries or death
brandVariant Ambien self-linksurface differs
surface form: Ambien CR
commonSideEffect dizziness
drowsiness
headache
nausea
contraindication known hypersensitivity to zolpidem
developer Sanofi
dosageForm extended-release tablet
immediate-release tablet
firstApprovalAgency Food and Drug Administration
surface form: U.S. Food and Drug Administration
firstApprovalRegion United States of America
surface form: United States
halfLife approximately 2 to 3 hours in healthy adults
hasActiveIngredient zolpidem tartrate
hasGenericName Ambien self-linksurface differs
surface form: zolpidem
indication short-term treatment of insomnia
legalStatusUS Schedule IV controlled substance
mechanismOfAction enhances GABA-mediated neuronal inhibition
metabolism hepatic
metabolizedBy CYP3A4
onsetOfAction rapid
pharmacologicalClass imidazopyridine derivative
non-benzodiazepine hypnotic
pregnancyCategoryUS C
primaryEffect helps people fall asleep more quickly
regulatoryStatus prescription-only medication
risk dependence
tolerance
withdrawal symptoms
routeOfAdministration oral
selectivity preferentially binds GABA-A receptors containing the alpha-1 subunit
seriousSideEffect abnormal thinking and behavioral changes
complex sleep behaviors
sleep-driving
sleepwalking
therapeuticArea sleep medicine
treatmentDuration recommended for short-term use
treats insomnia
typicalUse taken at bedtime
warning avoid use with alcohol
caution in elderly patients
caution in patients with respiratory impairment

How these facts were elicited

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

Ambien hasGenericName Ambien self-linksurface differs
this entity surface form: zolpidem
Ambien brandVariant Ambien self-linksurface differs
this entity surface form: Ambien CR