Wegener's granulomatosis

E105929

autoimmune disease granulomatous disease rare disease systemic vasculitis

Wegener's granulomatosis, now more commonly called granulomatosis with polyangiitis, is a rare autoimmune disease characterized by inflammation of blood vessels that can damage organs such as the lungs, kidneys, and upper respiratory tract.

Try in SPARQL Jump to: Surface forms Statements Referenced by

All labels observed (7)

Label	Occurrences
granulomatosis with polyangiitis	3
ANCA-associated vasculitis	1
Wegener	1
Wegener granulomatosis	1
Wegener vasculitis	1
Wegener's granulomatosis canonical	1
granulomatosis with polyangiitis (Wegener's)	1

Statements (65)

Predicate	Object
instanceOf	autoimmune disease ⓘ granulomatous disease ⓘ rare disease ⓘ systemic vasculitis ⓘ
affectsSystem	lower respiratory tract ⓘ renal system ⓘ respiratory system ⓘ upper respiratory tract ⓘ vascular system ⓘ
associatedWithAntibody	anti-proteinase 3 antibody ⓘ
canCause	chronic sinusitis ⓘ glomerulonephritis ⓘ hematuria ⓘ otitis media ⓘ proteinuria ⓘ pulmonary hemorrhage ⓘ pulmonary nodules ⓘ saddle-nose deformity ⓘ
hasAbbreviation	GPA ⓘ
hasBiomarker	PR3-ANCA ⓘ c-ANCA ⓘ
hasClassification	Wegener's granulomatosis self-linksurface differs ⓘ surface form: ANCA-associated vasculitis small-vessel vasculitis ⓘ
hasCourse	chronic relapsing course ⓘ
hasDiagnosticTest	ANCA test ⓘ chest CT scan ⓘ tissue biopsy ⓘ urinalysis ⓘ
hasEponym	Friedrich Wegener ⓘ
hasEtiology	autoimmune mechanism ⓘ
hasICD10Code	M31.3 ⓘ
hasPathologyFeature	medium-vessel vasculitis ⓘ necrotizing granulomatous inflammation ⓘ necrotizing vasculitis ⓘ small-vessel vasculitis ⓘ
hasPreferredName	Wegener's granulomatosis self-linksurface differs ⓘ surface form: granulomatosis with polyangiitis
hasPrognosis	potentially life-threatening ⓘ
hasSymptom	arthralgia ⓘ cough ⓘ dyspnea ⓘ epistaxis ⓘ fatigue ⓘ fever ⓘ hemoptysis ⓘ nasal congestion ⓘ weight loss ⓘ
hasSynonym	Wegener's granulomatosis self-linksurface differs ⓘ surface form: Wegener granulomatosis Wegener's granulomatosis self-linksurface differs ⓘ surface form: Wegener vasculitis Wegener's granulomatosis self-linksurface differs ⓘ surface form: granulomatosis with polyangiitis (Wegener's)
hasTreatmentPhase	induction therapy ⓘ maintenance therapy ⓘ
moreCommonIn	adults ⓘ middle-aged individuals ⓘ
recognizedBy	American College of Rheumatology ⓘ Chapel Hill Consensus Conference on Vasculitis Nomenclature ⓘ
treatedWith	azathioprine ⓘ cyclophosphamide ⓘ glucocorticoids ⓘ methotrexate ⓘ mycophenolate mofetil ⓘ Rituxan ⓘ surface form: rituximab
typicalLesionSite	kidneys ⓘ lungs ⓘ nasal cavity ⓘ paranasal sinuses ⓘ

Referenced by (9)

Full triples — surface form annotated when it differs from this entity's canonical label.

Heinrich Hertz → causeOfDeath → Wegener's granulomatosis ⓘ

Wegener's granulomatosis → hasPreferredName → Wegener's granulomatosis self-linksurface differs ⓘ

this entity surface form: granulomatosis with polyangiitis

Wegener's granulomatosis → hasSynonym → Wegener's granulomatosis self-linksurface differs ⓘ

this entity surface form: granulomatosis with polyangiitis (Wegener's)

Wegener's granulomatosis → hasSynonym → Wegener's granulomatosis self-linksurface differs ⓘ

this entity surface form: Wegener granulomatosis

Wegener's granulomatosis → hasSynonym → Wegener's granulomatosis self-linksurface differs ⓘ

this entity surface form: Wegener vasculitis

Wegener's granulomatosis → hasClassification → Wegener's granulomatosis self-linksurface differs ⓘ

this entity surface form: ANCA-associated vasculitis

Ruxience → isUsedForTreatmentOf → Wegener's granulomatosis ⓘ

this entity surface form: granulomatosis with polyangiitis

Riabni → hasIndication → Wegener's granulomatosis ⓘ

this entity surface form: granulomatosis with polyangiitis

Gerda Wegener → familyName → Wegener's granulomatosis ⓘ

this entity surface form: Wegener