immune checkpoint receptor
C59321
concept
An immune checkpoint receptor is a cell-surface protein, typically on immune cells like T cells, that modulates immune responses by delivering inhibitory or stimulatory signals upon binding to its ligand, thereby maintaining self-tolerance and preventing overactivation.
All labels observed (2)
| Label | Occurrences |
|---|---|
| immune checkpoint receptor canonical | 2 |
| inhibitory co-receptor | 1 |
Description generation (CDg)
The one-sentence description above was generated by prompting gpt-5.1 with the class name and this instruction.
Instruction
generate a one-sentence description for a given conceptual class. # Response Format Return only the sentence: "Description: [one-sentence description of the conceptional class]"
Input
Class: immune checkpoint receptor
Generated description
An immune checkpoint receptor is a cell-surface protein, typically on immune cells like T cells, that modulates immune responses by delivering inhibitory or stimulatory signals upon binding to its ligand, thereby maintaining self-tolerance and preventing overactivation.
Instances (3)
| Instance | Via concept surface |
|---|---|
| programmed cell death protein 1 | — |
| PD-1 | — |
| CD22 | inhibitory co-receptor |