immune checkpoint receptor
C59321
concept
An immune checkpoint receptor is a cell-surface protein, typically on immune cells like T cells, that modulates immune responses by delivering inhibitory or stimulatory signals upon binding to its ligand, thereby maintaining self-tolerance and preventing overactivation.
Observed surface forms (1)
- inhibitory co-receptor ×1
Instances (3)
- programmed cell death protein 1
- PD-1
- CD22 via concept surface "inhibitory co-receptor"