Triple

T10837750
Position Surface form Disambiguated ID Type / Status
Subject Bruton tyrosine kinase E255805 entity
Predicate activatedBy P6232 FINISHED
Object Src family kinases
Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
E888596 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Src family kinases | Statement: [Bruton tyrosine kinase, activatedBy, Src family kinases]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Src family kinases
Context triple: [Bruton tyrosine kinase, activatedBy, Src family kinases]
  • A. ABC subfamily B
    ABC subfamily B is a group of ATP-binding cassette (ABC) transporters that typically function as membrane proteins involved in the translocation of various molecules across cellular membranes and often contribute to multidrug resistance.
  • B. PKC
    PKC is a leading international cryptography conference focused on public-key cryptography research and advancements.
  • C. PKC
    PKC is the IATA airport code for Petropavlovsk-Kamchatsky Airport, a major air gateway to Russia’s Kamchatka Peninsula.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. SYK
    SYK is the stock ticker symbol for Stryker Corporation, a major U.S.-based medical technology company specializing in surgical equipment, orthopedics, and related healthcare products.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Src family kinases
Triple: [Bruton tyrosine kinase, activatedBy, Src family kinases]
Generated description
Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Src family kinases
Target entity description: Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
  • A. ABC subfamily B
    ABC subfamily B is a group of ATP-binding cassette (ABC) transporters that typically function as membrane proteins involved in the translocation of various molecules across cellular membranes and often contribute to multidrug resistance.
  • B. PKC
    PKC is a leading international cryptography conference focused on public-key cryptography research and advancements.
  • C. PKC
    PKC is the IATA airport code for Petropavlovsk-Kamchatsky Airport, a major air gateway to Russia’s Kamchatka Peninsula.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. SYK
    SYK is the stock ticker symbol for Stryker Corporation, a major U.S.-based medical technology company specializing in surgical equipment, orthopedics, and related healthcare products.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d6aa81a5d08190aa86689061d1ddd2 completed April 8, 2026, 7:20 p.m.
NER Named-entity recognition batch_69d747002b3081908726901ee83d8f38 completed April 9, 2026, 6:28 a.m.
NED1 Entity disambiguation (via context triple) batch_69deb139072081908a67e76a83575c32 completed April 14, 2026, 9:27 p.m.
NEDg Description generation batch_69deb41c9ae881909a3dab1292d6ddd7 completed April 14, 2026, 9:39 p.m.
NED2 Entity disambiguation (via description) batch_69deb4e471648190a00f3a921b5fb657 completed April 14, 2026, 9:43 p.m.
Created at: April 8, 2026, 9:19 p.m.