Triple

T10291855
Position Surface form Disambiguated ID Type / Status
Subject BCRP E241383 entity
Predicate encodedBy P14248 FINISHED
Object ABCG2 gene
The ABCG2 gene encodes a membrane transporter protein involved in multidrug resistance and the efflux of various xenobiotics and endogenous compounds across cellular membranes.
E856800 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: ABCG2 gene | Statement: [BCRP, encodedBy, ABCG2 gene]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: ABCG2 gene
Context triple: [BCRP, encodedBy, ABCG2 gene]
  • A. P-glycoprotein
    P-glycoprotein is a membrane-bound efflux transporter protein that pumps various drugs and xenobiotics out of cells, influencing their absorption, distribution, and resistance profiles.
  • B. CYP2D6
    CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
  • C. CYP3A4
    CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
  • D. CYP1A2
    CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
  • E. CYP2C19
    CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: ABCG2 gene
Triple: [BCRP, encodedBy, ABCG2 gene]
Generated description
The ABCG2 gene encodes a membrane transporter protein involved in multidrug resistance and the efflux of various xenobiotics and endogenous compounds across cellular membranes.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: ABCG2 gene
Target entity description: The ABCG2 gene encodes a membrane transporter protein involved in multidrug resistance and the efflux of various xenobiotics and endogenous compounds across cellular membranes.
  • A. P-glycoprotein
    P-glycoprotein is a membrane-bound efflux transporter protein that pumps various drugs and xenobiotics out of cells, influencing their absorption, distribution, and resistance profiles.
  • B. CYP2D6
    CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
  • C. CYP3A4
    CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
  • D. CYP1A2
    CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
  • E. CYP2C19
    CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d381aaafc08190af475ef58dc16aba completed April 6, 2026, 9:49 a.m.
NER Named-entity recognition batch_69d4d2d35f048190a215493acdf1f718 completed April 7, 2026, 9:48 a.m.
NED1 Entity disambiguation (via context triple) batch_69d7500fdd1c81909395469afb346f8b completed April 9, 2026, 7:06 a.m.
NEDg Description generation batch_69d75133588c819093af59327b951cd7 completed April 9, 2026, 7:11 a.m.
NED2 Entity disambiguation (via description) batch_69d751d4aa908190a825322ebf0066af completed April 9, 2026, 7:14 a.m.
Created at: April 6, 2026, 11:42 a.m.