hasAminoAcidChange
P61676
predicate
Indicates that an entity (such as a protein or gene variant) involves or results in a specific change from one amino acid to another in its sequence.
All labels observed (3)
| Label | Occurrences |
|---|---|
| hasProteinMutation | 3 |
| Val158MetEffect | 1 |
| hasAminoAcidChange canonical | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: hasAminoAcidChange
Generated description
Indicates that an entity (such as a protein or gene variant) involves or results in a specific change from one amino acid to another in its sequence.
Sample triples (5)
| Subject | Object |
|---|---|
| APOE ε4 allele | arginine at positions 112 and 158 of apolipoprotein E ⓘ |
| Delta variant | L452R via predicate surface "hasProteinMutation" ⓘ |
| Delta variant | T478K via predicate surface "hasProteinMutation" ⓘ |
| Delta variant | P681R via predicate surface "hasProteinMutation" ⓘ |
| catechol-O-methyltransferase | alters enzymatic activity and thermostability via predicate surface "Val158MetEffect" ⓘ |