Kocher sign
E91527
Kocher sign is a clinical indicator associated with hyperthyroidism, particularly Graves' disease, characterized by a lag of the upper eyelid on downward gaze.
Observed surface forms (2)
| Surface form | Occurrences |
|---|---|
| Dalrymple sign | 1 |
| von Graefe sign | 1 |
Statements (35)
| Predicate | Object |
|---|---|
| instanceOf |
clinical sign
ⓘ
medical eponym ⓘ |
| associatedWith |
Graves disease
ⓘ
hyperthyroidism ⓘ thyrotoxicosis ⓘ |
| clinicalRelevance |
helps differentiate Graves disease from other causes of thyrotoxicosis
ⓘ
suggests active thyroid disease ⓘ |
| countryOfOrigin | Switzerland ⓘ |
| describes | lag of upper eyelid on downward gaze ⓘ |
| differsFrom |
Kocher sign
self-linksurface differs
ⓘ
surface form:
Dalrymple sign
Stellwag sign ⓘ Kocher sign self-linksurface differs ⓘ
surface form:
von Graefe sign
|
| firstDescribedBy | Emil Theodor Kocher ⓘ |
| firstDescribedIn | 19th century ⓘ |
| foundIn |
endocrinology examination
ⓘ
ophthalmic examination ⓘ |
| hasCategory |
endocrine sign
ⓘ
ophthalmologic sign ⓘ |
| hasFeature |
eyelid lag on downgaze
ⓘ
infrequent blinking ⓘ retraction of upper eyelid ⓘ staring appearance ⓘ upper eyelid fails to follow eyeball promptly on downward movement ⓘ widened palpebral fissure ⓘ |
| namedAfter |
Emil Theodor Kocher
ⓘ
Emil Theodor Kocher ⓘ
surface form:
Theodor Kocher
|
| observedDuring | patient following examiner’s finger from upward to downward gaze ⓘ |
| partOf |
Graves ophthalmopathy signs
ⓘ
eye signs of hyperthyroidism ⓘ |
| pathophysiology | increased sympathetic tone to Müller muscle of upper eyelid ⓘ |
| relatedTo |
lid lag
ⓘ
lid retraction ⓘ sympathetic overactivity ⓘ |
| usedFor |
clinical diagnosis of Graves ophthalmopathy
ⓘ
supporting diagnosis of hyperthyroidism ⓘ |
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
von Graefe sign
this entity surface form:
Dalrymple sign