Virchow–Robin spaces

E71210

Virchow–Robin spaces are perivascular, fluid-filled spaces that surround blood vessels as they penetrate the brain, visible on neuroimaging and often associated with various neurological conditions.


Statements (49)
Predicate Object
instanceOf anatomical structure
neuroanatomical feature
perivascular space
alsoKnownAs perivascular Virchow–Robin spaces
perivascular spaces
are fluid-filled spaces
normal anatomical finding
pial-lined spaces
associatedWith Parkinson disease
aging
cerebral amyloid angiopathy
cerebral small vessel disease
cognitive impairment
dementia
glymphatic system dysfunction
hypertension
lacunar infarcts
migraine
multiple sclerosis
traumatic brain injury
white matter hyperintensities
boundedBy pia mater
vascular adventitia
canBe enlarged
incidental finding on neuroimaging
commonLocation basal ganglia
centrum semiovale
hippocampus
midbrain
contain interstitial fluid
differentialDiagnosisIncludes cystic neoplasm
lacunar infarct
neuroepithelial cyst
doNotEnhanceWith gadolinium contrast on MRI
enlargementAssociatedWith neurodegeneration
neuroinflammation
vascular risk factors
filledWith cerebrospinal fluid-like fluid
location brain
central nervous system
namedAfter Charles Philippe Robin
Rudolf Virchow
roleIn interstitial fluid drainage
waste clearance from brain parenchyma
signalCharacteristic CSF-like signal on MRI
surround small penetrating blood vessels
visibleOn MRI FLAIR images
MRI T2-weighted images
magnetic resonance imaging

Referenced by (3)
Subject (surface form when different) Predicate
Virchow–Robin spaces ("perivascular spaces")
Virchow–Robin spaces ("perivascular Virchow–Robin spaces")
alsoKnownAs
Rudolf Virchow
hasEponym

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