Plegridy
E24878
Plegridy is a pegylated interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
Statements (51)
| Predicate | Object |
|---|---|
| instanceOf |
disease-modifying therapy
ⓘ
medication ⓘ pegylated interferon beta-1a ⓘ |
| activeIngredient | peginterferon beta-1a ⓘ |
| belongsToClass |
immunomodulatory agents
ⓘ
interferon beta-1a ⓘ |
| hasAdministrationFrequency | every 14 days ⓘ |
| hasApprovalAuthority |
European Medicines Agency
ⓘ
Food and Drug Administration ⓘ
surface form:
U.S. Food and Drug Administration
|
| hasATCCode | L03AB13 ⓘ |
| hasBlackBoxWarning |
risk of depression and suicide
ⓘ
risk of hepatotoxicity ⓘ |
| hasCommonSideEffect |
chills
ⓘ
flu-like symptoms ⓘ headache ⓘ injection site reactions ⓘ myalgia ⓘ pyrexia ⓘ |
| hasContraindication |
history of suicidal ideation
ⓘ
severe depression ⓘ severe hepatic impairment ⓘ |
| hasDeveloper | Biogen ⓘ |
| hasDosageForm |
pre-filled pen
ⓘ
pre-filled syringe ⓘ solution for injection ⓘ |
| hasEffect |
reduces MRI lesion activity
ⓘ
reduces relapse rate in multiple sclerosis ⓘ slows disability progression ⓘ |
| hasLegalStatusEU | prescription only ⓘ |
| hasLegalStatusUS | prescription only ⓘ |
| hasManufacturer | Biogen ⓘ |
| hasMechanismOfAction |
immunomodulation
ⓘ
reduction of inflammatory responses in multiple sclerosis ⓘ |
| hasPregnancyCategoryUS | C ⓘ |
| hasRouteOfAdministration |
subcutaneous
ⓘ
subcutaneous injection ⓘ |
| hasSeriousSideEffect |
depression
ⓘ
hepatotoxicity ⓘ pulmonary arterial hypertension ⓘ suicidal ideation ⓘ thrombotic microangiopathy ⓘ |
| hasTradeName | Plegridy self-link ⓘ |
| isAdministeredTo | adults ⓘ |
| isPegylated | true ⓘ |
| isUsedFor | long-term treatment of multiple sclerosis ⓘ |
| treats |
active secondary progressive multiple sclerosis
ⓘ
clinically isolated syndrome ⓘ relapsing forms of multiple sclerosis ⓘ relapsing-remitting multiple sclerosis ⓘ |
| wasApprovedInEU | 2014 ⓘ |
| wasApprovedInUS | 2014 ⓘ |
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.