Study 301
E125384
Study 301 is a pivotal clinical trial evaluating the efficacy and safety of the Alzheimer’s disease drug Leqembi (lecanemab) in patients with early-stage disease.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Study 301 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T1103716 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Study 301 Context triple: [Leqembi, hasKeyClinicalTrial, Study 301]
-
A.
Backlog Studies
Backlog Studies is a collection of humorous and reflective essays by American writer Charles Dudley Warner, known for its charming depictions of domestic life and nature.
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B.
Stuvsta
Stuvsta is a residential district and commuter suburb in the southern Stockholm area of Sweden, known for its villas, local center, and good rail connections to central Stockholm.
-
C.
Stroop Report
The Stroop Report is a detailed Nazi account compiled by SS General Jürgen Stroop that chronicles and photographs the brutal suppression and destruction of the Warsaw Ghetto and its Jewish resistance.
-
D.
Hawthorne studies
The Hawthorne studies were a series of influential workplace experiments conducted in the 1920s–1930s that revealed how social and psychological factors significantly affect employee productivity and behavior.
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E.
Cram
Cram is a surname most notably associated with Ralph Adams Cram, a prominent American architect known for his influential Gothic Revival designs.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Study 301 Target entity description: Study 301 is a pivotal clinical trial evaluating the efficacy and safety of the Alzheimer’s disease drug Leqembi (lecanemab) in patients with early-stage disease.
-
A.
Backlog Studies
Backlog Studies is a collection of humorous and reflective essays by American writer Charles Dudley Warner, known for its charming depictions of domestic life and nature.
-
B.
Stuvsta
Stuvsta is a residential district and commuter suburb in the southern Stockholm area of Sweden, known for its villas, local center, and good rail connections to central Stockholm.
-
C.
Stroop Report
The Stroop Report is a detailed Nazi account compiled by SS General Jürgen Stroop that chronicles and photographs the brutal suppression and destruction of the Warsaw Ghetto and its Jewish resistance.
-
D.
Hawthorne studies
The Hawthorne studies were a series of influential workplace experiments conducted in the 1920s–1930s that revealed how social and psychological factors significantly affect employee productivity and behavior.
-
E.
Cram
Cram is a surname most notably associated with Ralph Adams Cram, a prominent American architect known for his influential Gothic Revival designs.
- F. None of above. chosen
Statements (13)
| Predicate | Object |
|---|---|
| instanceOf |
clinical trial
ⓘ
phase 3 trial ⓘ pivotal trial ⓘ |
| assesses |
efficacy
ⓘ
safety ⓘ |
| diseaseStage | early-stage Alzheimer’s disease ⓘ |
| evaluatesDrug |
Leqembi
ⓘ
Leqembi ⓘ
surface form:
lecanemab
|
| indication |
Alzheimer's disease
ⓘ
surface form:
Alzheimer’s disease
|
| sponsorDrugBrand | Leqembi ⓘ |
| sponsorDrugGeneric |
Leqembi
ⓘ
surface form:
lecanemab
|
| targetPopulation | patients with early-stage Alzheimer’s disease ⓘ |
| therapeuticClass | anti-amyloid monoclonal antibody ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Study 301 Description of subject: Study 301 is a pivotal clinical trial evaluating the efficacy and safety of the Alzheimer’s disease drug Leqembi (lecanemab) in patients with early-stage disease.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.