azole antifungal

C46436
concept

Azole antifungals are a class of drugs that inhibit fungal ergosterol synthesis by blocking cytochrome P450–dependent 14α-demethylase, thereby disrupting cell membrane formation and treating a variety of fungal infections.

All labels observed (2)

Label Occurrences
azole antifungal canonical 5
imidazole derivative 1

Description generation (CDg)

The one-sentence description above was generated by prompting gpt-5.1 with the class name and this instruction.

Instruction
generate a one-sentence description for a given conceptual class.
# Response Format
Return only the sentence: "Description: [one-sentence description of the conceptional class]"
Input
Class: azole antifungal
Generated description
Azole antifungals are a class of drugs that inhibit fungal ergosterol synthesis by blocking cytochrome P450–dependent 14α-demethylase, thereby disrupting cell membrane formation and treating a variety of fungal infections.

Instances (5)

Instance Via concept surface
voriconazole
posaconazole
fluconazole
ketoconazole imidazole derivative
itraconazole