Triple

T6005948
Position Surface form Disambiguated ID Type / Status
Subject Neurospora crassa E133709 entity
Predicate historicallyImportantExperiment P9764 FINISHED
Object one gene–one enzyme hypothesis
The one gene–one enzyme hypothesis is a foundational concept in genetics proposing that each gene encodes a specific enzyme that affects a single step in a metabolic pathway.
E561767 NE FINISHED

How this triple was built (5 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: one gene–one enzyme hypothesis | Statement: [Neurospora crassa, historicallyImportantExperiment, one gene–one enzyme hypothesis]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: one gene–one enzyme hypothesis
Context triple: [Neurospora crassa, historicallyImportantExperiment, one gene–one enzyme hypothesis]
  • A. The Theory of the Gene
    The Theory of the Gene is a foundational 1926 book by geneticist Thomas Hunt Morgan that synthesized experimental evidence to establish chromosomes and genes as the physical basis of heredity.
  • B. Molecular Biology of the Gene
    Molecular Biology of the Gene is a landmark molecular biology textbook, co-authored by James Watson, that helped define and systematize modern understanding of DNA structure, gene function, and genetic regulation.
  • C. Haldane–Oparin hypothesis of the origin of life
    The Haldane–Oparin hypothesis of the origin of life proposes that life first arose through a gradual chemical evolution of organic molecules in Earth’s early “primordial soup,” eventually leading to self-replicating systems.
  • D. Luria–Delbrück experiment
    The Luria–Delbrück experiment was a landmark 1943 study in bacterial genetics that demonstrated mutations arise randomly rather than in response to selective pressure, providing key evidence for the genetic basis of evolution.
  • E. The Mechanism of Mendelian Heredity
    The Mechanism of Mendelian Heredity is a foundational early 20th-century genetics book that established the chromosome theory of inheritance through experimental work with fruit flies.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: one gene–one enzyme hypothesis
Triple: [Neurospora crassa, historicallyImportantExperiment, one gene–one enzyme hypothesis]
Generated description
The one gene–one enzyme hypothesis is a foundational concept in genetics proposing that each gene encodes a specific enzyme that affects a single step in a metabolic pathway.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: one gene–one enzyme hypothesis
Target entity description: The one gene–one enzyme hypothesis is a foundational concept in genetics proposing that each gene encodes a specific enzyme that affects a single step in a metabolic pathway.
  • A. The Theory of the Gene
    The Theory of the Gene is a foundational 1926 book by geneticist Thomas Hunt Morgan that synthesized experimental evidence to establish chromosomes and genes as the physical basis of heredity.
  • B. Molecular Biology of the Gene
    Molecular Biology of the Gene is a landmark molecular biology textbook, co-authored by James Watson, that helped define and systematize modern understanding of DNA structure, gene function, and genetic regulation.
  • C. Haldane–Oparin hypothesis of the origin of life
    The Haldane–Oparin hypothesis of the origin of life proposes that life first arose through a gradual chemical evolution of organic molecules in Earth’s early “primordial soup,” eventually leading to self-replicating systems.
  • D. Luria–Delbrück experiment
    The Luria–Delbrück experiment was a landmark 1943 study in bacterial genetics that demonstrated mutations arise randomly rather than in response to selective pressure, providing key evidence for the genetic basis of evolution.
  • E. The Mechanism of Mendelian Heredity
    The Mechanism of Mendelian Heredity is a foundational early 20th-century genetics book that established the chromosome theory of inheritance through experimental work with fruit flies.
  • F. None of above. chosen
PD Predicate disambiguation gpt-5-mini-2025-08-07
Target predicate: historicallyImportantExperiment
Context triple: [Neurospora crassa, historicallyImportantExperiment, one gene–one enzyme hypothesis]
  • A. historicalExperiment chosen
    Indicates that an experiment was conducted in the past and is of historical significance or relevance.
  • B. notableExperiment
    Indicates that an entity is recognized for having conducted or been the subject of a particularly important or influential experiment.
  • C. majorExperiment
    Indicates that an entity conducts or is involved in a primary, large-scale, or most significant experiment in a given context.
  • D. experimentedOn
    Indicates that one entity conducted experiments or tests on another entity as the subject of investigation.
  • E. eraOfScience
    Indicates that one entity is a historical period characterized by particular developments or features in science associated with the other entity.
  • F. None of above.

Provenance (6 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69c00872444c8190bfaf1739dcec765c completed March 22, 2026, 3:19 p.m.
NER Named-entity recognition batch_69c04f128354819088971ee398cbda77 completed March 22, 2026, 8:20 p.m.
NED1 Entity disambiguation (via context triple) batch_69c10895559081908b9efdd32ecef37f completed March 23, 2026, 9:32 a.m.
NEDg Description generation batch_69c10b7467e88190955014bc060b20e4 completed March 23, 2026, 9:44 a.m.
NED2 Entity disambiguation (via description) batch_69c10c0a001c81908e3ca53e9491ff9a completed March 23, 2026, 9:46 a.m.
PD Predicate disambiguation batch_69c049e4daf4819099bf870dc700e0a2 completed March 22, 2026, 7:58 p.m.
Created at: March 22, 2026, 4:06 p.m.