Triple

T6005141
Position Surface form Disambiguated ID Type / Status
Subject Tegsedi E133690 entity
Predicate coDevelopedBy P3324 FINISHED
Object Akcea Therapeutics
Akcea Therapeutics is a biopharmaceutical company focused on developing RNA-targeted therapies for rare and serious diseases, particularly in the cardiometabolic and hereditary amyloidosis space.
E561116 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Akcea Therapeutics | Statement: [Tegsedi, coDevelopedBy, Akcea Therapeutics]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Akcea Therapeutics
Context triple: [Tegsedi, coDevelopedBy, Akcea Therapeutics]
  • A. Alkermes
    Alkermes is a biopharmaceutical company that develops innovative medicines for central nervous system disorders and other serious chronic diseases.
  • B. AbbVie
    AbbVie is a global biopharmaceutical company known for developing and marketing innovative therapies in areas such as immunology, oncology, and neuroscience.
  • C. Regeneron Pharmaceuticals
    Regeneron Pharmaceuticals is a leading American biotechnology company known for developing innovative antibody-based therapies for serious diseases, including eye disorders, cancer, and inflammatory conditions.
  • D. Vertex Pharmaceuticals
    Vertex Pharmaceuticals is a biotechnology company best known for developing transformative therapies for cystic fibrosis and other serious diseases using a precision medicine approach.
  • E. Biogen
    Biogen is a major American biotechnology company known for developing therapies for neurological and neurodegenerative diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Akcea Therapeutics
Triple: [Tegsedi, coDevelopedBy, Akcea Therapeutics]
Generated description
Akcea Therapeutics is a biopharmaceutical company focused on developing RNA-targeted therapies for rare and serious diseases, particularly in the cardiometabolic and hereditary amyloidosis space.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Akcea Therapeutics
Target entity description: Akcea Therapeutics is a biopharmaceutical company focused on developing RNA-targeted therapies for rare and serious diseases, particularly in the cardiometabolic and hereditary amyloidosis space.
  • A. Alkermes
    Alkermes is a biopharmaceutical company that develops innovative medicines for central nervous system disorders and other serious chronic diseases.
  • B. AbbVie
    AbbVie is a global biopharmaceutical company known for developing and marketing innovative therapies in areas such as immunology, oncology, and neuroscience.
  • C. Regeneron Pharmaceuticals
    Regeneron Pharmaceuticals is a leading American biotechnology company known for developing innovative antibody-based therapies for serious diseases, including eye disorders, cancer, and inflammatory conditions.
  • D. Vertex Pharmaceuticals
    Vertex Pharmaceuticals is a biotechnology company best known for developing transformative therapies for cystic fibrosis and other serious diseases using a precision medicine approach.
  • E. Biogen
    Biogen is a major American biotechnology company known for developing therapies for neurological and neurodegenerative diseases.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69c00872444c8190bfaf1739dcec765c completed March 22, 2026, 3:19 p.m.
NER Named-entity recognition batch_69c04f10d18081908c351170b7f58d3d completed March 22, 2026, 8:20 p.m.
NED1 Entity disambiguation (via context triple) batch_69c1088f5c84819094e4696c24c4dd79 completed March 23, 2026, 9:31 a.m.
NEDg Description generation batch_69c1099f00f88190a5f1f0fafbb679c2 completed March 23, 2026, 9:36 a.m.
NED2 Entity disambiguation (via description) batch_69c10a2ffdcc8190bfeebc59d98b2b29 completed March 23, 2026, 9:38 a.m.
Created at: March 22, 2026, 4:06 p.m.