Triple

T6003524
Position Surface form Disambiguated ID Type / Status
Subject Verzenio E133651 entity
Predicate targets P860 FINISHED
Object CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
E561032 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CDK4 | Statement: [Verzenio, targets, CDK4]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: CDK4
Context triple: [Verzenio, targets, CDK4]
  • A. Cdc28
    Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
  • B. CNK4
    CNK4 is the ICAO airport code assigned to Parry Sound Area Municipal Airport in Ontario, Canada.
  • C. ERBB2
    ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
  • D. ERK
    ERK is the abbreviation for the Evangelical Reformed Church, a Protestant regional church within the Reformed tradition.
  • E. HER2 receptor
    The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: CDK4
Triple: [Verzenio, targets, CDK4]
Generated description
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: CDK4
Target entity description: CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • A. Cdc28
    Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
  • B. CNK4
    CNK4 is the ICAO airport code assigned to Parry Sound Area Municipal Airport in Ontario, Canada.
  • C. ERBB2
    ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
  • D. ERK
    ERK is the abbreviation for the Evangelical Reformed Church, a Protestant regional church within the Reformed tradition.
  • E. HER2 receptor
    The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69c00872444c8190bfaf1739dcec765c completed March 22, 2026, 3:19 p.m.
NER Named-entity recognition batch_69c04f0f63148190826198281dce3713 completed March 22, 2026, 8:20 p.m.
NED1 Entity disambiguation (via context triple) batch_69c1088f5c84819094e4696c24c4dd79 completed March 23, 2026, 9:31 a.m.
NEDg Description generation batch_69c1099f00f88190a5f1f0fafbb679c2 completed March 23, 2026, 9:36 a.m.
NED2 Entity disambiguation (via description) batch_69c10a2ffdcc8190bfeebc59d98b2b29 completed March 23, 2026, 9:38 a.m.
Created at: March 22, 2026, 4:06 p.m.