Triple

T6003489
Position Surface form Disambiguated ID Type / Status
Subject Alimta E133650 entity
Predicate targetsEnzyme P37016 FINISHED
Object glycinamide ribonucleotide formyltransferase
Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
E561031 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: glycinamide ribonucleotide formyltransferase | Statement: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: glycinamide ribonucleotide formyltransferase
Context triple: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
  • A. Flavin
    Flavin is a surname most notably associated with American minimalist artist Dan Flavin, renowned for his fluorescent light installations.
  • B. DNA ligase
    DNA ligase is an essential enzyme that joins breaks in the sugar-phosphate backbone of DNA, enabling processes such as DNA replication and genetic recombination.
  • C. Edman
    Edman is a masculine given name most notably borne by Edman Spangler, a carpenter implicated in the conspiracy surrounding U.S. President Abraham Lincoln’s assassination.
  • D. GFATM
    GFATM is a global financing institution that mobilizes and invests resources to combat HIV/AIDS, tuberculosis, and malaria in low- and middle-income countries.
  • E. Gi protein
    Gi protein is a subtype of heterotrimeric G protein that inhibits adenylyl cyclase activity and modulates various intracellular signaling pathways when activated by G protein–coupled receptors.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: glycinamide ribonucleotide formyltransferase
Triple: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
Generated description
Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: glycinamide ribonucleotide formyltransferase
Target entity description: Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
  • A. Flavin
    Flavin is a surname most notably associated with American minimalist artist Dan Flavin, renowned for his fluorescent light installations.
  • B. DNA ligase
    DNA ligase is an essential enzyme that joins breaks in the sugar-phosphate backbone of DNA, enabling processes such as DNA replication and genetic recombination.
  • C. Edman
    Edman is a masculine given name most notably borne by Edman Spangler, a carpenter implicated in the conspiracy surrounding U.S. President Abraham Lincoln’s assassination.
  • D. GFATM
    GFATM is a global financing institution that mobilizes and invests resources to combat HIV/AIDS, tuberculosis, and malaria in low- and middle-income countries.
  • E. Gi protein
    Gi protein is a subtype of heterotrimeric G protein that inhibits adenylyl cyclase activity and modulates various intracellular signaling pathways when activated by G protein–coupled receptors.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69c00872444c8190bfaf1739dcec765c completed March 22, 2026, 3:19 p.m.
NER Named-entity recognition batch_69c0560bae148190ad4755defaaf471b completed March 22, 2026, 8:50 p.m.
NED1 Entity disambiguation (via context triple) batch_69c1088f5c84819094e4696c24c4dd79 completed March 23, 2026, 9:31 a.m.
NEDg Description generation batch_69c1099f00f88190a5f1f0fafbb679c2 completed March 23, 2026, 9:36 a.m.
NED2 Entity disambiguation (via description) batch_69c10a2ffdcc8190bfeebc59d98b2b29 completed March 23, 2026, 9:38 a.m.
Created at: March 22, 2026, 4:06 p.m.