Triple
T6003489
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Alimta |
E133650
|
entity |
| Predicate | targetsEnzyme |
P37016
|
FINISHED |
| Object |
glycinamide ribonucleotide formyltransferase
Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
|
E561031
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: glycinamide ribonucleotide formyltransferase | Statement: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: glycinamide ribonucleotide formyltransferase Context triple: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
-
A.
Flavin
Flavin is a surname most notably associated with American minimalist artist Dan Flavin, renowned for his fluorescent light installations.
-
B.
DNA ligase
DNA ligase is an essential enzyme that joins breaks in the sugar-phosphate backbone of DNA, enabling processes such as DNA replication and genetic recombination.
-
C.
Edman
Edman is a masculine given name most notably borne by Edman Spangler, a carpenter implicated in the conspiracy surrounding U.S. President Abraham Lincoln’s assassination.
-
D.
GFATM
GFATM is a global financing institution that mobilizes and invests resources to combat HIV/AIDS, tuberculosis, and malaria in low- and middle-income countries.
-
E.
Gi protein
Gi protein is a subtype of heterotrimeric G protein that inhibits adenylyl cyclase activity and modulates various intracellular signaling pathways when activated by G protein–coupled receptors.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: glycinamide ribonucleotide formyltransferase Triple: [Alimta, targetsEnzyme, glycinamide ribonucleotide formyltransferase]
Generated description
Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: glycinamide ribonucleotide formyltransferase Target entity description: Glycinamide ribonucleotide formyltransferase is a key enzyme in the de novo purine biosynthesis pathway that catalyzes a formylation step essential for nucleotide production and is targeted by certain anticancer drugs.
-
A.
Flavin
Flavin is a surname most notably associated with American minimalist artist Dan Flavin, renowned for his fluorescent light installations.
-
B.
DNA ligase
DNA ligase is an essential enzyme that joins breaks in the sugar-phosphate backbone of DNA, enabling processes such as DNA replication and genetic recombination.
-
C.
Edman
Edman is a masculine given name most notably borne by Edman Spangler, a carpenter implicated in the conspiracy surrounding U.S. President Abraham Lincoln’s assassination.
-
D.
GFATM
GFATM is a global financing institution that mobilizes and invests resources to combat HIV/AIDS, tuberculosis, and malaria in low- and middle-income countries.
-
E.
Gi protein
Gi protein is a subtype of heterotrimeric G protein that inhibits adenylyl cyclase activity and modulates various intracellular signaling pathways when activated by G protein–coupled receptors.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69c00872444c8190bfaf1739dcec765c |
completed | March 22, 2026, 3:19 p.m. |
| NER | Named-entity recognition | batch_69c0560bae148190ad4755defaaf471b |
completed | March 22, 2026, 8:50 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69c1088f5c84819094e4696c24c4dd79 |
completed | March 23, 2026, 9:31 a.m. |
| NEDg | Description generation | batch_69c1099f00f88190a5f1f0fafbb679c2 |
completed | March 23, 2026, 9:36 a.m. |
| NED2 | Entity disambiguation (via description) | batch_69c10a2ffdcc8190bfeebc59d98b2b29 |
completed | March 23, 2026, 9:38 a.m. |
Created at: March 22, 2026, 4:06 p.m.