Triple
T36599357
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | lapatinib |
E902877
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | HER2 inhibitor |
C43617
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: HER2 inhibitor Context triple: [lapatinib, instanceOf, HER2 inhibitor]
-
A.
EGFR inhibitor
An EGFR inhibitor is a drug that blocks the epidermal growth factor receptor signaling pathway to slow or stop the growth of cancer cells that depend on this receptor.
-
B.
CDK4/6 inhibitor
A CDK4/6 inhibitor is a targeted anticancer drug that blocks cyclin-dependent kinases 4 and 6 to halt cell cycle progression from G1 to S phase, thereby inhibiting tumor cell proliferation.
-
C.
PARP inhibitor
A PARP inhibitor is a targeted anticancer drug that blocks poly(ADP-ribose) polymerase enzymes to prevent DNA repair in tumor cells, leading to their death, particularly in cancers with existing DNA repair defects such as BRCA-mutated tumors.
-
D.
tyrosine kinase inhibitor
chosen
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
-
E.
IGF-1R inhibitor
An IGF-1R inhibitor is a drug that blocks the insulin-like growth factor 1 receptor to reduce signaling pathways that promote cell growth, survival, and proliferation, particularly in cancer cells.
- F. None of above.
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f76e66b7b88190848f7a3e1188915f |
completed | May 3, 2026, 3:48 p.m. |
Created at: May 3, 2026, 4:11 p.m.