tyrosine kinase inhibitor
C43617
concept
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
All labels observed (7)
| Label | Occurrences |
|---|---|
| tyrosine kinase inhibitor canonical | 10 |
| protein kinase inhibitor | 6 |
| HER2 inhibitor | 3 |
| RET inhibitor | 1 |
| TRK inhibitor | 1 |
| anaplastic lymphoma kinase inhibitor | 1 |
| small-molecule tyrosine kinase inhibitor | 1 |
Description generation (CDg)
The one-sentence description above was generated by prompting gpt-5.1 with the class name and this instruction.
Instruction
generate a one-sentence description for a given conceptual class. # Response Format Return only the sentence: "Description: [one-sentence description of the conceptional class]"
Input
Class: tyrosine kinase inhibitor
Generated description
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
Instances (15)
| Instance | Via concept surface |
|---|---|
| Tagrisso | — |
| larotrectinib | — |
| selpercatinib | — |
| LOXO-292 | — |
| Vitrakvi | — |
| Retevmo | — |
| LOXO-195 | TRK inhibitor |
| Gleevec | — |
| Tasigna | — |
| Alecensa | protein kinase inhibitor |
| acalabrutinib | protein kinase inhibitor |
| zanubrutinib | protein kinase inhibitor |
| lapatinib | — |
| neratinib | — |
| tucatinib | small-molecule tyrosine kinase inhibitor |