Triple

Target class: seven-transmembrane receptor
Context triple: [M2 muscarinic acetylcholine receptor, instanceOf, seven-transmembrane receptor]

• A. transmembrane receptor
  A transmembrane receptor is a membrane-spanning protein that detects extracellular signals and transduces them into specific intracellular responses.
• B. G protein–coupled receptor chosen
  A G protein–coupled receptor is a membrane-spanning protein that detects extracellular signals and activates intracellular G proteins to trigger specific cellular responses.
• C. heterotrimeric G protein
  A heterotrimeric G protein is a membrane-associated signaling protein complex composed of three distinct subunits (α, β, and γ) that transduces signals from activated G protein–coupled receptors to intracellular effector pathways by cycling between GDP-bound inactive and GTP-bound active states.
• D. receptor tyrosine kinase
  A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
• E. cannabinoid receptor
  A cannabinoid receptor is a cell-surface G protein–coupled receptor that binds endogenous, plant-derived, or synthetic cannabinoids to modulate processes such as pain perception, appetite, mood, and immune function.
• F. None of above.