Triple
T33205834
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | clarithromycin |
E850012
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | CYP3A5 inhibitor |
C58227
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: CYP3A5 inhibitor Context triple: [clarithromycin, instanceOf, CYP3A5 inhibitor]
-
A.
CYP3A4 inhibitor
chosen
A CYP3A4 inhibitor is a substance that decreases the metabolic activity of the cytochrome P450 3A4 enzyme, thereby increasing the plasma concentration and effects of drugs metabolized by this pathway.
-
B.
BCRP inhibitor
A BCRP inhibitor is a compound that reduces or blocks the activity of the Breast Cancer Resistance Protein (ABCG2) efflux transporter, thereby altering the absorption, distribution, and elimination of its substrate drugs.
-
C.
NS5A inhibitor
An NS5A inhibitor is an antiviral drug that targets the nonstructural protein 5A of hepatitis C virus, disrupting viral RNA replication and assembly to prevent viral proliferation.
-
D.
DPP-4 inhibitor
A DPP-4 inhibitor is a medication that blocks the dipeptidyl peptidase-4 enzyme to increase incretin levels, thereby enhancing insulin secretion and lowering blood glucose in people with type 2 diabetes.
-
E.
CDK4/6 inhibitor
A CDK4/6 inhibitor is a targeted anticancer drug that blocks cyclin-dependent kinases 4 and 6 to halt cell cycle progression from G1 to S phase, thereby inhibiting tumor cell proliferation.
- F. None of above.
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f3495fb92c819083ce65d0ddee7a76 |
completed | April 30, 2026, 12:21 p.m. |
Created at: May 1, 2026, 1:30 a.m.