Triple
T32196277
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | PD-1 |
E822412
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | inhibitory receptor |
C29138
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: inhibitory receptor Context triple: [PD-1, instanceOf, inhibitory receptor]
-
A.
immune checkpoint ligand
An immune checkpoint ligand is a molecule, typically expressed on the surface of cells, that binds to corresponding immune checkpoint receptors to modulate and often inhibit immune cell activation and maintain immune homeostasis.
-
B.
receptor tyrosine kinase
A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
-
C.
transmembrane receptor
chosen
A transmembrane receptor is a membrane-spanning protein that detects extracellular signals and transduces them into specific intracellular responses.
-
D.
Bruton’s tyrosine kinase
Bruton’s tyrosine kinase is a non-receptor tyrosine kinase crucial for B-cell receptor signaling, development, and function, and is a key therapeutic target in certain autoimmune diseases and B-cell malignancies.
-
E.
checkpoint inhibitor
A checkpoint inhibitor is a type of drug that blocks immune checkpoint proteins, thereby enhancing the immune system’s ability to recognize and attack cancer cells.
- F. None of above.
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f349093174819086e633c190a51aa8 |
completed | April 30, 2026, 12:20 p.m. |
Created at: May 1, 2026, 12:36 a.m.