Triple
T23650336
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Gleevec |
E584150
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | protein kinase inhibitor |
C43617
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: protein kinase inhibitor Context triple: [Gleevec, instanceOf, protein kinase inhibitor]
-
A.
tyrosine kinase inhibitor
chosen
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
-
B.
proteasome inhibitor
A proteasome inhibitor is a compound that blocks the activity of cellular proteasomes, preventing the degradation of ubiquitinated proteins and thereby disrupting key regulatory pathways, often used as an anticancer strategy.
-
C.
cyclin-dependent kinase
A cyclin-dependent kinase is an enzyme that regulates progression through the cell cycle by phosphorylating specific target proteins in a manner dependent on binding to cyclins.
-
D.
receptor tyrosine kinase
A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
-
E.
Janus kinase inhibitor
A Janus kinase inhibitor is a drug that selectively blocks Janus kinase (JAK) enzymes to modulate cytokine signaling and reduce inflammation or abnormal immune activity in various diseases.
- F. None of above.
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e248fefafc81909656921192f30e80 |
completed | April 17, 2026, 2:51 p.m. |
Created at: April 17, 2026, 6:49 p.m.