Triple
T22796786
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | CDK6 |
E564269
|
entity |
| Predicate | isDrugTargetOf |
P37016
|
FINISHED |
| Object | palbociclib |
—
|
NE NERFINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: palbociclib | Statement: [CDK6, isDrugTargetOf, palbociclib]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: palbociclib Context triple: [CDK6, isDrugTargetOf, palbociclib]
-
A.
Ibrance
chosen
Ibrance is a targeted oral cancer medication (palbociclib) used primarily to treat certain types of hormone receptor–positive, HER2-negative advanced or metastatic breast cancer.
-
B.
lapatinib
Lapatinib is an oral small-molecule tyrosine kinase inhibitor used primarily to treat HER2-positive breast cancer.
-
C.
trilaciclib
Trilaciclib is an intravenous cyclin-dependent kinase 4/6 inhibitor used to protect bone marrow from chemotherapy-induced damage in patients with certain cancers.
-
D.
Lynparza
Lynparza is a targeted cancer therapy (a PARP inhibitor) used primarily to treat certain types of ovarian, breast, pancreatic, and prostate cancers associated with BRCA mutations.
-
E.
Talycopa
Talycopa is a locality or area within the community of Llansamlet in Swansea, Wales.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: isDrugTargetOf Context triple: [CDK6, isDrugTargetOf, palbociclib]
-
A.
isTherapeuticTargetIn
Indicates that a biological entity (e.g., gene, protein, pathway) is used or proposed as a therapeutic target within a specified disease, condition, or treatment context.
-
B.
hasMolecularTarget
chosen
Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
-
C.
hasTargetDisease
Indicates that an entity (such as a treatment, study, or intervention) is directed toward, intended to affect, or primarily concerned with a specified disease.
-
D.
hasDrugBankID
Indicates that an entity is associated with a specific identifier from the DrugBank database.
-
E.
regulatoryTarget
Indicates that one entity is subject to control, influence, or governance by another entity under a regulatory or rule-based framework.
- F. None of above.
Provenance (3 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2458185f88190b0045227ee420411 |
completed | April 17, 2026, 2:36 p.m. |
| NER | Named-entity recognition | batch_69f17cd9b3c0819096050f43a829ec0d |
completed | April 29, 2026, 3:36 a.m. |
| PD | Predicate disambiguation | batch_69eed2c32e8c8190b73bb9965ed47d64 |
completed | April 27, 2026, 3:06 a.m. |
Created at: April 17, 2026, 3:30 p.m.