Triple
T22690564
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | BTK |
E561038
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | Bruton’s tyrosine kinase |
C46687
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: Bruton’s tyrosine kinase Context triple: [BTK, instanceOf, Bruton’s tyrosine kinase]
-
A.
Bruton tyrosine kinase inhibitor
A Bruton tyrosine kinase inhibitor is a targeted small-molecule drug that blocks BTK signaling in B cells to disrupt pathways critical for their activation, proliferation, and survival, primarily used in the treatment of certain B-cell malignancies and autoimmune diseases.
-
B.
Janus kinase inhibitor
A Janus kinase inhibitor is a drug that selectively blocks Janus kinase (JAK) enzymes to modulate cytokine signaling and reduce inflammation or abnormal immune activity in various diseases.
-
C.
receptor tyrosine kinase
A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
-
D.
tyrosine kinase inhibitor
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
-
E.
cluster of differentiation antigen
A cluster of differentiation antigen is a cell surface molecule used as a marker to identify and classify leukocyte subsets and other cell types, often serving functional roles in cell signaling and immune responses.
- F. None of above. chosen
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
Created at: April 17, 2026, 3:13 p.m.