Triple
T22690296
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | CDK4 |
E561032
|
entity |
| Predicate | regulatedBy |
P86
|
FINISHED |
| Object | CDKN2A (p16INK4A) |
—
|
NE NERFINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CDKN2A (p16INK4A) | Statement: [CDK4, regulatedBy, CDKN2A (p16INK4A)]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CDKN2A (p16INK4A) Context triple: [CDK4, regulatedBy, CDKN2A (p16INK4A)]
-
A.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
B.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
C.
Cdh1
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
PTEN
PTEN is a tumor suppressor gene encoding a phosphatase that negatively regulates the PI3K/AKT signaling pathway and is frequently mutated in various human cancers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: CDKN2A (p16INK4A) Target entity description: CDKN2A (p16INK4A) is a tumor suppressor gene encoding a cyclin-dependent kinase inhibitor that controls cell cycle progression and is frequently inactivated in human cancers.
-
A.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
B.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
C.
Cdh1
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
PTEN
PTEN is a tumor suppressor gene encoding a phosphatase that negatively regulates the PI3K/AKT signaling pathway and is frequently mutated in various human cancers.
- F. None of above. chosen
Provenance (2 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1789a1fd08190bce5fa0babe695d3 |
completed | April 29, 2026, 3:18 a.m. |
Created at: April 17, 2026, 3:13 p.m.