Triple

Target class: serine/threonine protein kinase
Context triple: [Cdc28, instanceOf, serine/threonine protein kinase]

• A. receptor tyrosine kinase
  A receptor tyrosine kinase is a transmembrane protein that, upon binding an extracellular ligand, dimerizes and autophosphorylates its intracellular tyrosine residues to initiate intracellular signaling cascades regulating cell growth, differentiation, and survival.
• B. heterotrimeric G protein
  A heterotrimeric G protein is a membrane-associated signaling protein complex composed of three distinct subunits (α, β, and γ) that transduces signals from activated G protein–coupled receptors to intracellular effector pathways by cycling between GDP-bound inactive and GTP-bound active states.
• C. G protein–coupled receptor
  A G protein–coupled receptor is a membrane-spanning protein that detects extracellular signals and activates intracellular G proteins to trigger specific cellular responses.
• D. tyrosine kinase inhibitor
  A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
• E. protein chosen
  A protein is a large, complex biological molecule composed of one or more chains of amino acids that fold into specific three-dimensional structures to perform diverse structural, catalytic, signaling, and regulatory functions in living organisms.
• F. None of above.